2-(2-Bromo-5-(difluoromethyl)-4-hydroxypyridin-3-yl)acetonitrile CAS 1804660-56-7

Purity 97%+In StockPharmaceutical Standards
CAS No.1804660-56-7
Molecular FormulaC8H5BrF2N2O
Molecular Weight263.04 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-(2-Bromo-5-(difluoromethyl)-4-hydroxypyridin-3-yl)acetonitrile CAS 1804660-56-7 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 263.04 g/mol gives 2-(2-Bromo-5-(difluoromethyl)-4-hydroxypyridin-3-yl)acetonitrile distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

2-(2-Bromo-5-(difluoromethyl)-4-hydroxypyridin-3-yl)acetonitrile (CAS 1804660-56-7), molecular formula C8H5BrF2N2O and molecular weight 263.04 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 2-(2-Bromo-5-(difluoromethyl)-4-hydroxypyridin-3-yl)acetonitrile (C8H5BrF2N2O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.

As a certified reference material (CRM), 2-(2-Bromo-5-(difluoromethyl)-4-hydroxypyridin-3-yl)acetonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC8H5BrF2N2O
Molecular Weight263.04 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1995
Halogen ContentF/Br-containing
Nitrogen Atoms2

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