6-(Difluoromethyl)-2-formyl-3-nitroisonicotinonitrile CAS 1804692-00-9

Purity 97%+In StockPharmaceutical Standards
CAS No.1804692-00-9
Molecular FormulaC8H3F2N3O3
Molecular Weight227.12 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

6-(Difluoromethyl)-2-formyl-3-nitroisonicotinonitrile CAS 1804692-00-9 chemical structure

Description

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

6-(Difluoromethyl)-2-formyl-3-nitroisonicotinonitrile (CAS 1804692-00-9), molecular formula C8H3F2N3O3 and molecular weight 227.12 g/mol, is a CATO reference standard with documented purity and traceability.

6-(Difluoromethyl)-2-formyl-3-nitroisonicotinonitrile (C8H3F2N3O3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

As a certified reference material (CRM), 6-(Difluoromethyl)-2-formyl-3-nitroisonicotinonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC8H3F2N3O3
Molecular Weight227.12 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, ethanol, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1995
Halogen ContentF-containing
Nitrogen Atoms3

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