4-Amino-6-chloro-5-(difluoromethyl)picolinonitrile CAS 1804697-66-2
| CAS No. | 1804697-66-2 |
| Molecular Formula | C7H4ClF2N3 |
| Molecular Weight | 203.58 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to a nitrile group, fluorine/chlorine substitution, an aromatic ring system, 4-Amino-6-chloro-5-(difluoromethyl)picolinonitrile is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 203.58 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
4-Amino-6-chloro-5-(difluoromethyl)picolinonitrile (CAS 1804697-66-2), molecular formula C7H4ClF2N3 and molecular weight 203.58 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4-Amino-6-chloro-5-(difluoromethyl)picolinonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H4ClF2N3 |
| Molecular Weight | 203.58 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related Amino Standards
- Methyl 3-amino-6-chloro-5-hydroxypyrazine-2-carboxylate (CAS 1503-04-4)
- 2-Amino-4-chloro-6-(difluoromethyl)nicotinonitrile (CAS 1803670-02-1)
- 4-Amino-2-chloro-5-(difluoromethyl)nicotinonitrile (CAS 1804697-58-2)
- 2-Amino-4-chloro-5-(difluoromethyl)nicotinonitrile (CAS 1805055-95-1)
- 6-Amino-3-chloro-5-(difluoromethyl)picolinonitrile (CAS 1805335-46-9)
- 4-Amino-3-chloro-6-(difluoromethyl)picolinonitrile (CAS 1805335-58-3)
- 6-Amino-4-chloro-5-(difluoromethyl)nicotinonitrile (CAS 1806068-76-7)
- 4-Amino-6-chloro-2-(difluoromethyl)nicotinonitrile (CAS 1806806-62-1)
Recommended Standards
- 2-Chloro-4-ethoxy-5-nitropyrimidine (CAS 1702077-93-7)
- 5-Chloro-4-methoxy-2-nitrophenol (CAS 14164-14-8)
- 6-Chloro-4-(difluoromethyl)-1H-pyrazolo[3,4-b]pyridine (CAS 1279829-79-6)
- 6-Amino-5-chloro-3-(difluoromethyl)picolinonitrile (CAS 1806815-70-2)
- (5S,7S,8S)-8-(((benzyloxy)carbonyl)amino)-4,4-dimethyl-1-oxaspiro[4.4]Nonane-7-carboxylic acid (CAS 2243168-07-0)
- 2-fluoro-6-iodo-4-(trifluoromethyl)aniline (CAS 1217304-64-7)
- 8ZZ2GU5WBU 6091-50-5 Piperitone, D- 2-Cyclohexen-1-one, 3-methyl-6-(1-methylethyl)-, (S)- 2-Cyclohexen-1-one, 3-methyl-6-(1-methyethyl)-, (S)- FEMA No. 2910 4-Isopropyl-1-methyl-1-cyclohexen-3-one p-Menth-1-en-3-one 1-Methyl-4-isopropyl-1-cyclohexen-3-one 3-Methyl-6-(1-methylethyl)-2-cyclohexen-1-one, (S)- Piperitone, alpha- d-Piperitone d-Piperitone (natural) UNII-8ZZ2GU5WBU (CAS 6091-50-5)
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