4-(Difluoromethyl)-5-fluoro-6-(hydroxymethyl)pyridin-2-ol CAS 1804701-62-9
| CAS No. | 1804701-62-9 |
| Molecular Formula | C7H6F3NO2 |
| Molecular Weight | 193.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-(Difluoromethyl)-5-fluoro-6-(hydroxymethyl)pyridin-2-ol.
4-(Difluoromethyl)-5-fluoro-6-(hydroxymethyl)pyridin-2-ol (CAS 1804701-62-9), molecular formula C7H6F3NO2 and molecular weight 193.12 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 4-(Difluoromethyl)-5-fluoro-6-(hydroxymethyl)pyridin-2-ol (C7H6F3NO2) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 4.0, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 193.12 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 4-(Difluoromethyl)-5-fluoro-6-(hydroxymethyl)pyridin-2-ol under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H6F3NO2 |
| Molecular Weight | 193.12 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Difluoromethyl Standards
- 4-(Difluoromethyl)-5-fluoro-3-methoxypyridin-2-ol (CAS 1805035-78-2)
- 2-(Difluoromethyl)-3-fluoro-6-hydroxypyridine-4-methanol (CAS 1805036-43-4)
- 2-(Difluoromethyl)-3-fluoro-5-hydroxypyridine-6-methanol (CAS 1805432-34-1)
- 2-(Difluoromethyl)-5-fluoro-4-hydroxypyridine-3-methanol (CAS 1805432-39-6)
- 4-(Difluoromethyl)-2-fluoro-6-methoxypyridin-3-ol (CAS 1805476-70-3)
- 4-(Difluoromethyl)-3-fluoro-6-methoxypyridin-2-ol (CAS 1805476-77-0)
- 4-(Difluoromethyl)-5-fluoro-2-(hydroxymethyl)pyridin-3-ol (CAS 1805478-44-7)
- 2-(Difluoromethyl)-4-fluoro-5-hydroxy-3-methoxypyridine (CAS 1805483-69-5)
Recommended Standards
- 6-(Hydroxymethyl)-4-(trifluoromethyl)pyridin-2(1H)-one (CAS 1804438-08-1)
- (4-(Difluoromethoxy)-3-fluoropyridin-2-yl)methanol (CAS 1803838-37-0)
- 5-Methyl-2-(trifluoromethyl)furan-3-carboxamide (CAS 175276-68-3)
- Methyl 3-(Trifluoromethyl)pyrrole-2-carboxylate (CAS 1628642-61-4)
- 2-(6-Oxo-5-(2-(pentyloxy)benzylidene)-5,6-dihydrothiazolo[3,2-b][1,2,4]triazol-2-yl)phenyl acetate (CAS 617694-63-0)
- N-Hydroxy-2-[methyl(tetrahydro-2H-pyran-4-ylmethyl)amino]benzenecarboximidamide (CAS 1220040-43-6)
- Tris(2,4,6-triisopropylphenyl)gallium (CAS 146658-80-2)
- 1,7-Difluoroheptan-2-One (CAS 333-06-2)
- methyl 3-({[amino(4-bromophenyl)methylidene]amino}oxy)prop-2-enoate (CAS 1461727-01-4)
- N-(2-(1,3-dimethyl-5-phenoxy-1H-pyrazol-4-yl)ethyl)-3-methylbutanamide (CAS 956437-86-8)
- 3-Benzyloxy-2-chloro-6-fluorophenylboronic acid (CAS 957062-67-8)
- 2,6-Dichloro-N-(2-(methylamino)ethyl)nicotinamide hydrochloride (CAS 2314362-48-4)
- tert-Butyl 3-(bromomethyl)-5-(trifluoromethyl)-1H-indole-1-carboxylate (CAS 1823499-57-5)
- Semaglutide impurity 276 (CAS CATO-C4X-2226276)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com