2-(Difluoromethyl)-4-fluoro-3-iodopyridine-5-methanol CAS 1804705-45-0
| CAS No. | 1804705-45-0 |
| Molecular Formula | C7H5F3INO |
| Molecular Weight | 303.02 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-(Difluoromethyl)-4-fluoro-3-iodopyridine-5-methanol (CAS 1804705-45-0), molecular formula C7H5F3INO and molecular weight 303.02 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-(Difluoromethyl)-4-fluoro-3-iodopyridine-5-methanol (C7H5F3INO) is characterized by an amide group, a hydroxyl group, an ether linkage, fluorine/iodine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 2-(Difluoromethyl)-4-fluoro-3-iodopyridine-5-methanol under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H5F3INO |
| Molecular Weight | 303.02 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F/I-containing |
| Nitrogen Atoms | 1 |
Related Difluoromethyl Standards
- 2-(Difluoromethyl)-4-fluoro-6-iodo-3-methoxypyridine (CAS 1804704-20-8)
- 4-(Difluoromethyl)-2-fluoro-3-iodo-5-methoxypyridine (CAS 1804704-29-7)
- 2-(Difluoromethyl)-6-fluoro-5-iodopyridine-3-methanol (CAS 1804705-50-7)
- 2-(Difluoromethyl)-5-fluoro-3-iodopyridine-4-methanol (CAS 1805049-78-8)
- 2-(Difluoromethyl)-6-fluoro-4-iodopyridine-3-methanol (CAS 1805049-82-4)
- (4-(Difluoromethyl)-6-fluoro-5-iodopyridin-2-yl)methanol (CAS 1805050-38-7)
- 2-(Difluoromethyl)-4-fluoro-3-iodopyridine-6-methanol (CAS 1805292-45-8)
- 4-(Difluoromethyl)-3-fluoro-2-iodo-5-methoxypyridine (CAS 1805480-52-7)
Recommended Standards
- 2-Iodo-6-methoxy-4-(trifluoromethyl)pyridine (CAS 1805027-39-7)
- 5-Iodo-4-methoxy-2-(trifluoromethyl)pyridine (CAS 1804437-74-8)
- 5-Iodo-3-methoxy-2-(trifluoromethyl)pyridine (CAS 1803797-15-0)
- 3-Iodo-4-(trifluoromethoxy)aniline (CAS 1365969-58-9)
- 1-2-3-6-Tetra-O-pivaloyl-α-D-galactofuranoside (CAS 220017-49-2)
- (S)-1-(tetrahydrofuran-3-yl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole (CAS 1809837-95-3)
- Bz-Arg-βNA · HCl (CAS 198555-19-0)
- [(4-Methylquinolin-2-yl)sulfanyl]acetic acid (CAS 17880-62-5)
- (3-Cyanobenzyl)triphenylphosphonium bromide (CAS 169503-38-2)
- 6-(Piperazin-1-yl)hexan-1-amine (CAS 115986-20-4)
- 2-Butenedioic acid (2E)-, di-C12-14-alkyl esters, polymers with Et vinyl ether and vinyl acetate (CAS 68988-67-0)
- 4H,5H-imidazo[1,2-a]quinazolin-5-one (CAS 109224-70-6)
- 4-Amino-4-(5-bromothiophen-2-yl)butanoic acid (CAS 1250224-42-0)
- Semaglutide impurity 80 (CAS CATO-C4X-222680)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com