2-(Difluoromethyl)-6-methoxy-5-(trifluoromethoxy)pyridine-3-acetic acid CAS 1805009-45-3

Purity 97%+In StockPharmaceutical Standards
CAS No.1805009-45-3
Molecular FormulaC10H8F5NO4
Molecular Weight301.17 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-(Difluoromethyl)-6-methoxy-5-(trifluoromethoxy)pyridine-3-acetic acid CAS 1805009-45-3 chemical structure

Description

The occurrence of 2-(Difluoromethyl)-6-methoxy-5-(trifluoromethoxy)pyridine-3-acetic acid is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

CATO supplies 2-(Difluoromethyl)-6-methoxy-5-(trifluoromethoxy)pyridine-3-acetic acid (CAS 1805009-45-3), a certified reference material (molecular formula C10H8F5NO4, MW 301.17 g/mol) for analytical method development and quality control.

2-(Difluoromethyl)-6-methoxy-5-(trifluoromethoxy)pyridine-3-acetic acid (C10H8F5NO4) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 2-(Difluoromethyl)-6-methoxy-5-(trifluoromethoxy)pyridine-3-acetic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC10H8F5NO4
Molecular Weight301.17 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in methanol, ethanol, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1995
Halogen ContentF-containing
Nitrogen Atoms1

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