1-Iodo-3-nitro-5-(trifluoromethoxy)benzene CAS 1805027-98-8
| CAS No. | 1805027-98-8 |
| Molecular Formula | C7H3F3INO3 |
| Molecular Weight | 333.00 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
1-Iodo-3-nitro-5-(trifluoromethoxy)benzene (CAS 1805027-98-8) is a high-purity analytical reference standard with the molecular formula C7H3F3INO3 and a molecular weight of 333.00 g/mol.
The molecular framework of 1-Iodo-3-nitro-5-(trifluoromethoxy)benzene (C7H3F3INO3) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/iodine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), 1-Iodo-3-nitro-5-(trifluoromethoxy)benzene meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H3F3INO3 |
| Molecular Weight | 333.00 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F/I-containing |
| Nitrogen Atoms | 1 |
Related Iodo Standards
- 1-Iodo-3-nitro-2-(trifluoromethoxy)benzene (CAS 1803738-58-0)
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