Ethyl 6-chloro-2-fluoro-3-(trifluoromethyl)benzoate CAS 1805034-38-1
| CAS No. | 1805034-38-1 |
| Molecular Formula | C10H7ClF4O2 |
| Molecular Weight | 270.61 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Ethyl 6-chloro-2-fluoro-3-(trifluoromethyl)benzoate (C10H7ClF4O2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO supplies Ethyl 6-chloro-2-fluoro-3-(trifluoromethyl)benzoate (CAS 1805034-38-1), a certified reference material (molecular formula C10H7ClF4O2, MW 270.61 g/mol) for analytical method development and quality control.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H7ClF4O2 |
| Molecular Weight | 270.61 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F/Cl-containing |
Related Ethyl Standards
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Recommended Standards
- 1-methyl-3,4-dinitro-1H-pyrazole-5-sulfonyl chloride (CAS 1803595-58-5)
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- 6-Chloro-2-(perfluoroethyl)-1H-benzo[d]imidazole (CAS 58457-67-3)
- 2-(4-Chloro-5-(difluoromethyl)-3-(trifluoromethyl)pyridin-2-yl)acetonitrile (CAS 1807126-64-2)
- 2-Bromo-[1,1'-biphenyl]-4-ol (CAS 15460-07-8)
- 774-89-0 ethyl (3-oxo-2-piperazinylidene)acetate ethyl 2-(3-oxo-2-piperazinylidene)acetate (CAS 774-89-0)
- 1-(Bromomethyl)-1-(3-(methylsulfonyl)propyl)cyclopropane (CAS 1466229-44-6)
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- 6-Bromo-8-methoxy-N,N,2-trimethylquinolin-4-amine (CAS 89446-16-2)
- 7-(4-Ethoxyphenyl)-4-methyl-2-(methylthio)-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidine (CAS 338416-18-5)
- (S)-5-Fluoro-1-(tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione (CAS 55774-30-6)
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- O-Ethyl 5-ethoxy-1-methyl-1H-pyrazole-4-carbothioate (CAS 146904-64-5)
- Semaglutide impurity 251 (CAS CATO-C4X-2226251)
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