4-Bromo-5-(difluoromethyl)-6-(trifluoromethyl)nicotinaldehyde CAS 1805044-57-8
| CAS No. | 1805044-57-8 |
| Molecular Formula | C8H3BrF5NO |
| Molecular Weight | 304.01 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-Bromo-5-(difluoromethyl)-6-(trifluoromethyl)nicotinaldehyde.
4-Bromo-5-(difluoromethyl)-6-(trifluoromethyl)nicotinaldehyde (CAS 1805044-57-8), molecular formula C8H3BrF5NO and molecular weight 304.01 g/mol, is a CATO reference standard with documented purity and traceability.
4-Bromo-5-(difluoromethyl)-6-(trifluoromethyl)nicotinaldehyde (C8H3BrF5NO) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4-Bromo-5-(difluoromethyl)-6-(trifluoromethyl)nicotinaldehyde meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H3BrF5NO |
| Molecular Weight | 304.01 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 1 |
Related Bromo Standards
- 6-Bromo-5-(difluoromethyl)-4-(trifluoromethyl)nicotinaldehyde (CAS 1804464-92-3)
- 6-Bromo-4-(difluoromethyl)-5-(trifluoromethyl)picolinaldehyde (CAS 1804464-95-6)
- 4-Bromo-5-(difluoromethyl)-2-(trifluoromethyl)pyridine-3-carboxaldehyde (CAS 1804487-00-0)
- 6-Bromo-4-(difluoromethyl)-5-(trifluoromethyl)nicotinaldehyde (CAS 1804493-88-6)
- 2-Bromo-5-(difluoromethyl)-3-(trifluoromethyl)isonicotinaldehyde (CAS 1804494-00-5)
- 4-Bromo-6-(difluoromethyl)-5-(trifluoromethyl)picolinaldehyde (CAS 1804494-57-2)
- 2-Bromo-4-(difluoromethyl)-6-(trifluoromethyl)nicotinaldehyde (CAS 1805261-27-1)
- 4-Bromo-2-(difluoromethyl)-6-(trifluoromethyl)nicotinaldehyde (CAS 1805261-51-1)
Recommended Standards
- 6-Bromo-5-(difluoromethyl)-4-(trifluoromethyl)picolinaldehyde (CAS 1805964-38-8)
- 4-Bromo-5-(difluoromethyl)-6-(trifluoromethyl)picolinaldehyde (CAS 1805965-43-8)
- 2-Iodo-4-(trifluoromethoxy)phenol (CAS 405517-54-6)
- 1,1-Dibromo-2-(4-isopropylphenyl)ethene (CAS 142521-08-2)
- 4-Ethyl-1H-imidazole-1,2-diamine (CAS 694432-04-7)
- 5-Amino-N-cyclohexyl-1-ethyl-N-methyl-1H-pyrazole-3-carboxamide (CAS 1856071-05-0)
- 122115-57-5 Ethyl 7-(3-fluorophenyl)-7-oxoheptanoate DTXSID20645573 (CAS 122115-57-5)
- Fasudil Impurity 28 (CAS 125398-82-5)
- 2,3-Dichloro-N,N-dimethylbenzamide (CAS 90526-00-4)
- 3-Hydroxy-5-methoxybenzofuran-2-carbonitrile (CAS 26475-00-3)
- (2-Nitrophenyl)hydrazine hydrochloride(1:x) (CAS 56413-75-3)
- Methanetetracarboxylic acid (CAS 193197-67-0)
- 2-(2-((2-(4-Fluorophenyl)-2-oxoethyl)thio)thiazol-4-yl)-N-(2-methoxyethyl)acetamide (CAS 946199-50-4)
- Insulin B (22-25) (CAS 34367-73-2)
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