5-Bromo-3-(difluoromethyl)-2-fluoropyridin-4-amine CAS 1805053-63-7

Purity 97%+In StockPharmaceutical Standards
CAS No.1805053-63-7
Molecular FormulaC6H4BrF3N2
Molecular Weight241.01 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

5-Bromo-3-(difluoromethyl)-2-fluoropyridin-4-amine CAS 1805053-63-7 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-Bromo-3-(difluoromethyl)-2-fluoropyridin-4-amine.

5-Bromo-3-(difluoromethyl)-2-fluoropyridin-4-amine (CAS 1805053-63-7) is a high-purity analytical reference standard with the molecular formula C6H4BrF3N2 and a molecular weight of 241.01 g/mol.

Owing to a nitrile group, fluorine/bromine substitution, an aromatic ring system, 5-Bromo-3-(difluoromethyl)-2-fluoropyridin-4-amine is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 241.01 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 5-Bromo-3-(difluoromethyl)-2-fluoropyridin-4-amine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC6H4BrF3N2
Molecular Weight241.01 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)4.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1995
Halogen ContentF/Br-containing
Nitrogen Atoms2

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