2-(Aminomethyl)-6-(difluoromethyl)-5-hydroxypyridine-3-carboxaldehyde CAS 1805072-30-3

Purity 97%+In StockPharmaceutical Standards
CAS No.1805072-30-3
Molecular FormulaC8H8F2N2O2
Molecular Weight202.16 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-(Aminomethyl)-6-(difluoromethyl)-5-hydroxypyridine-3-carboxaldehyde CAS 1805072-30-3 chemical structure

Description

Structurally, 2-(Aminomethyl)-6-(difluoromethyl)-5-hydroxypyridine-3-carboxaldehyde (C8H8F2N2O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 202.16 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

2-(Aminomethyl)-6-(difluoromethyl)-5-hydroxypyridine-3-carboxaldehyde (CAS 1805072-30-3), molecular formula C8H8F2N2O2 and molecular weight 202.16 g/mol, is a CATO reference standard with documented purity and traceability.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 2-(Aminomethyl)-6-(difluoromethyl)-5-hydroxypyridine-3-carboxaldehyde meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC8H8F2N2O2
Molecular Weight202.16 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1995
Halogen ContentF-containing
Nitrogen Atoms2

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