2-(Chloromethyl)-6-(difluoromethyl)-3-iodo-5-methylpyridine CAS 1805093-10-0
| CAS No. | 1805093-10-0 |
| Molecular Formula | C8H7ClF2IN |
| Molecular Weight | 317.50 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-(Chloromethyl)-6-(difluoromethyl)-3-iodo-5-methylpyridine.
CATO supplies 2-(Chloromethyl)-6-(difluoromethyl)-3-iodo-5-methylpyridine (CAS 1805093-10-0), a certified reference material (molecular formula C8H7ClF2IN, MW 317.50 g/mol) for analytical method development and quality control.
The molecular framework of 2-(Chloromethyl)-6-(difluoromethyl)-3-iodo-5-methylpyridine (C8H7ClF2IN) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine/iodine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-(Chloromethyl)-6-(difluoromethyl)-3-iodo-5-methylpyridine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H7ClF2IN |
| Molecular Weight | 317.50 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F/Cl/I-containing |
| Nitrogen Atoms | 1 |
Related Chloromethyl Standards
- 2-(Chloromethyl)-5-(difluoromethyl)-3-iodo-6-methylpyridine (CAS 1805535-23-2)
- 2-(Chloromethyl)-5-(difluoromethyl)-4-iodo-3-methylpyridine (CAS 1805548-01-9)
- 2-(Chloromethyl)-5-(difluoromethyl)-6-iodo-3-methylpyridine (CAS 1806950-24-2)
- 2-(Chloromethyl)-4-(difluoromethyl)-6-iodo-3-methylpyridine (CAS 1807093-60-2)
- 4-(Chloromethyl)-2-(4-(difluoromethoxy)-3-isopropoxyphenyl)oxazole (CAS 2103191-10-0)
- 1-(Chloromethyl)-1,2-dihydro-3H-benz[e]indole-3-carboxylic Acid 1,1-Dimethylethyl Ester 454713-41-8 N-Boc-1-chloromethyl-1,2-dihydro-3H-benzo[e]indole tert-Butyl 1-(Chloromethyl)-1,2-dihydro-3H-benzo[e]indole-3-carboxylate (CAS 454713-41-8)
- (1-(2-(Chloromethyl)phenyl)ethyl)triethoxysilane (CAS 93803-92-0)
- 5-(Chloromethyl)-3-(difluoromethyl)-6-iodopyridin-2-amine (CAS 1805213-89-1)
Recommended Standards
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- Methyl 4-bromo-2-chloro-5-(trifluoromethyl)benzoate (CAS 2167951-05-3)
- Methyl 2-bromo-5-chloro-4-(trifluoromethyl)benzoate (CAS 2169152-40-1)
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- 2,6-DIfluoropyridine-3,5-diol (CAS 2010955-41-4)
- 4-(2-(2-Hydroxy-3,5-dimethylphenyl)-2-oxoethyl)piperidine-2,6-dione (CAS 526-02-3)
- 3-(Aminomethyl)-5-phenylpyrazole (CAS 936940-08-8)
- 7-(3-Aminopyrrolidin-1-yl)-1-cyclopropyl-6,8-difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (CAS 99734-98-2)
- Semaglutide impurity 269 (CAS CATO-C4X-2226269)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com