4-(Difluoromethyl)-6-iodo-3-methylpyridine-2-sulfonyl chloride CAS 1805095-01-5
| CAS No. | 1805095-01-5 |
| Molecular Formula | C7H5ClF2INO2S |
| Molecular Weight | 367.54 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
4-(Difluoromethyl)-6-iodo-3-methylpyridine-2-sulfonyl chloride (CAS 1805095-01-5), molecular formula C7H5ClF2INO2S and molecular weight 367.54 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 4-(Difluoromethyl)-6-iodo-3-methylpyridine-2-sulfonyl chloride (C7H5ClF2INO2S) contains an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine/iodine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 4.0, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 367.54 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H5ClF2INO2S |
| Molecular Weight | 367.54 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F/Cl/I-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Difluoromethyl Standards
- 4-(Difluoromethyl)-6-iodo-5-methylpyridine-3-sulfonyl chloride (CAS 1804868-16-3)
- 2-(Difluoromethyl)-5-iodo-3-methylpyridine-4-sulfonyl chloride (CAS 1805266-89-0)
- 4-(Difluoromethyl)-5-iodo-6-methylpyridine-3-sulfonyl chloride (CAS 1805267-03-1)
- 2-(Difluoromethyl)-4-iodo-6-methylpyridine-3-sulfonyl chloride (CAS 1805421-99-1)
- 4-(Difluoromethyl)-5-iodo-6-methylpyridine-2-sulfonyl chloride (CAS 1805422-32-5)
- 4-(Difluoromethyl)-2-iodo-5-methylpyridine-3-sulfonyl chloride (CAS 1805608-27-8)
- 2-(Difluoromethyl)-6-iodo-5-methylpyridine-3-sulfonyl chloride (CAS 1806859-20-0)
- 2-(Difluoromethyl)-4-iodo-3-methylpyridine-6-sulfonyl chloride (CAS 1806982-62-6)
Recommended Standards
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- H-β-(7-Methoxycoumarin-4-yl)-Ala-OH (CAS 208660-68-8)
- Boc-NH-PEG11-CH2CH2N3 (CAS 2395004-21-2)
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- (E)-4-(3-(4-Fluorophenyl)-3-oxoprop-1-en-1-yl)benzonitrile (CAS 183241-46-5)
- 1-(2-Amino-1,3-thiazol-4-yl)-2-chloroethan-1-one hydrochloride (CAS 1461709-10-3)
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- 1-Ethyl-5-[(2-methylpropan-2-yl)oxycarbonyl]-6,7-dihydro-4H-triazolo[4,5-c]pyridine-7-carboxylic acid (CAS 1391733-65-5)
- Neuropeptide Y (free acid) (human, rat) trifluoroacetate salt (CAS 99575-89-0)
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