2-Bromo-3-cyano-5-(trifluoromethyl)benzenesulfonyl chloride CAS 1805100-78-0

Purity 97%+In StockPharmaceutical Standards
CAS No.1805100-78-0
Molecular FormulaC8H2BrClF3NO2S
Molecular Weight348.52 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-Bromo-3-cyano-5-(trifluoromethyl)benzenesulfonyl chloride CAS 1805100-78-0 chemical structure

Description

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO supplies 2-Bromo-3-cyano-5-(trifluoromethyl)benzenesulfonyl chloride (CAS 1805100-78-0), a certified reference material (molecular formula C8H2BrClF3NO2S, MW 348.52 g/mol) for analytical method development and quality control.

Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine/bromine substitution, 2-Bromo-3-cyano-5-(trifluoromethyl)benzenesulfonyl chloride is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 348.52 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC8H2BrClF3NO2S
Molecular Weight348.52 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1995
Halogen ContentF/Cl/Br-containing
Nitrogen Atoms1
Sulfur Atoms1

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