4-Amino-5-chloro-6-(difluoromethyl)pyridine-3-sulfonyl chloride CAS 1805101-69-2

Purity 97%+In StockPharmaceutical Standards
CAS No.1805101-69-2
Molecular FormulaC6H4Cl2F2N2O2S
Molecular Weight277.08 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

4-Amino-5-chloro-6-(difluoromethyl)pyridine-3-sulfonyl chloride CAS 1805101-69-2 chemical structure

Description

The occurrence of 4-Amino-5-chloro-6-(difluoromethyl)pyridine-3-sulfonyl chloride is closely related to an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

4-Amino-5-chloro-6-(difluoromethyl)pyridine-3-sulfonyl chloride (CAS 1805101-69-2), molecular formula C6H4Cl2F2N2O2S and molecular weight 277.08 g/mol, is a CATO reference standard with documented purity and traceability.

4-Amino-5-chloro-6-(difluoromethyl)pyridine-3-sulfonyl chloride (C6H4Cl2F2N2O2S) contains an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC6H4Cl2F2N2O2S
Molecular Weight277.08 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)4.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1995
Halogen ContentF/Cl-containing
Nitrogen Atoms2
Sulfur Atoms1

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