5-Chloro-3-(difluoromethyl)-6-iodopyridin-2-amine CAS 1805104-70-4
| CAS No. | 1805104-70-4 |
| Molecular Formula | C6H4ClF2IN2 |
| Molecular Weight | 304.46 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO supplies 5-Chloro-3-(difluoromethyl)-6-iodopyridin-2-amine (CAS 1805104-70-4), a certified reference material (molecular formula C6H4ClF2IN2, MW 304.46 g/mol) for analytical method development and quality control.
The molecular framework of 5-Chloro-3-(difluoromethyl)-6-iodopyridin-2-amine (C6H4ClF2IN2) is characterized by a nitrile group, fluorine/chlorine/iodine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), 5-Chloro-3-(difluoromethyl)-6-iodopyridin-2-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H4ClF2IN2 |
| Molecular Weight | 304.46 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F/Cl/I-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
- 1-Chloro-3-(difluoromethoxy)-2-iodobenzene (CAS 1261477-76-2)
- 2-Chloro-1-(difluoromethoxy)-4-iodobenzene (CAS 1261604-63-0)
- 1-Chloro-3-(difluoromethoxy)-5-iodobenzene (CAS 1261645-41-3)
- 1-Chloro-2-(difluoromethoxy)-3-iodobenzene (CAS 1261670-28-3)
- 4-Chloro-2-(difluoromethoxy)-1-iodobenzene (CAS 1261685-40-8)
- 1-Chloro-4-(difluoromethoxy)-2-iodobenzene (CAS 1261850-04-7)
- 6-Chloro-2-(difluoromethyl)-5-iodopyridin-3-amine (CAS 1803670-96-3)
- 4-Chloro-6-(difluoromethyl)-3-iodopyridin-2-amine (CAS 1804723-17-8)
Recommended Standards
- 2-Chloro-3-(difluoromethyl)-6-iodopyridin-4-amine (CAS 1805056-78-3)
- 4-Chloro-3-(difluoromethyl)-6-iodopyridin-2-amine (CAS 1805207-45-7)
- 6-Chloro-2-(difluoromethyl)-3-iodopyridin-4-amine (CAS 1805207-55-9)
- 4-Chloro-3-(difluoromethyl)-5-iodopyridin-2-amine (CAS 1805325-33-0)
- 2-Bromo-5-(4H-1,2,4-triazol-4-yl)benzoic acid (CAS 1203043-34-8)
- 3-iodo-1H-pyrrolo[2,3-β]pyridine (CAS 23616-57-1)
- tert-Butyl (2-(2-amino-N-cyclopropylacetamido)cyclohexyl)carbamate (CAS 1353966-76-3)
- 5-Bromo-2-methylbenzohydrazide (CAS 1194769-56-6)
- 4'-Fluoro-[1,1'-biphenyl]-4-thiol (CAS 200958-13-0)
- (1R,2S)-2-Methylcyclopentanamine Hydrochloride (CAS 102778-36-9)
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- 2-{[4-(aminomethyl)phenyl](methyl)amino}acetamide dihydrochloride (CAS 2044713-07-5)
- [α-Glu](Side Chain)-Semaglutide (CAS CATO-C4X-2226159)
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