4-Amino-2-(difluoromethyl)-6-hydroxypyridine-3-sulfonamide CAS 1805138-83-3

Purity 97%+In StockPharmaceutical Standards
CAS No.1805138-83-3
Molecular FormulaC6H7F2N3O3S
Molecular Weight239.20 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

4-Amino-2-(difluoromethyl)-6-hydroxypyridine-3-sulfonamide CAS 1805138-83-3 chemical structure

Description

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

4-Amino-2-(difluoromethyl)-6-hydroxypyridine-3-sulfonamide (CAS 1805138-83-3) is a high-purity analytical reference standard with the molecular formula C6H7F2N3O3S and a molecular weight of 239.20 g/mol.

4-Amino-2-(difluoromethyl)-6-hydroxypyridine-3-sulfonamide (C6H7F2N3O3S) contains an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

As a certified reference material (CRM), 4-Amino-2-(difluoromethyl)-6-hydroxypyridine-3-sulfonamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC6H7F2N3O3S
Molecular Weight239.20 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, ethanol, DMSO, water
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)4.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1995
Halogen ContentF-containing
Nitrogen Atoms3
Sulfur Atoms1

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