2-Cyano-4-(difluoromethyl)-6-iodopyridine-3-sulfonamide CAS 1805186-28-0

Purity 97%+In StockPharmaceutical Standards
CAS No.1805186-28-0
Molecular FormulaC7H4F2IN3O2S
Molecular Weight359.09 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-Cyano-4-(difluoromethyl)-6-iodopyridine-3-sulfonamide CAS 1805186-28-0 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-Cyano-4-(difluoromethyl)-6-iodopyridine-3-sulfonamide.

2-Cyano-4-(difluoromethyl)-6-iodopyridine-3-sulfonamide (CAS 1805186-28-0), molecular formula C7H4F2IN3O2S and molecular weight 359.09 g/mol, is a CATO reference standard with documented purity and traceability.

Structurally, 2-Cyano-4-(difluoromethyl)-6-iodopyridine-3-sulfonamide (C7H4F2IN3O2S) contains an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/iodine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 359.09 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 2-Cyano-4-(difluoromethyl)-6-iodopyridine-3-sulfonamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC7H4F2IN3O2S
Molecular Weight359.09 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1995
Halogen ContentF/I-containing
Nitrogen Atoms3
Sulfur Atoms1

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