2-(4-(Difluoromethyl)-6-fluoro-2-methoxypyridin-3-yl)acetic acid CAS 1805192-97-5
| CAS No. | 1805192-97-5 |
| Molecular Formula | C9H8F3NO3 |
| Molecular Weight | 235.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 2-(4-(Difluoromethyl)-6-fluoro-2-methoxypyridin-3-yl)acetic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies 2-(4-(Difluoromethyl)-6-fluoro-2-methoxypyridin-3-yl)acetic acid (CAS 1805192-97-5), a certified reference material (molecular formula C9H8F3NO3, MW 235.16 g/mol) for analytical method development and quality control.
The molecular framework of 2-(4-(Difluoromethyl)-6-fluoro-2-methoxypyridin-3-yl)acetic acid (C9H8F3NO3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C9H8F3NO3 |
| Molecular Weight | 235.16 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Difluoromethyl Standards
- 2-(Difluoromethyl)-5-fluoro-3-methoxypyridine-4-acetic acid (CAS 1804469-39-3)
- 2-(Difluoromethyl)-3-fluoro-6-methoxypyridine-4-acetic acid (CAS 1805442-12-9)
- 2-(4-(Difluoromethyl)-6-fluoro-5-methoxypyridin-3-yl)acetic acid (CAS 1805442-64-1)
- 2-(Difluoromethyl)-5-fluoro-3-methoxypyridine-6-acetic acid (CAS 1805529-69-4)
- 2-(4-(Difluoromethyl)-2-fluoro-5-methoxypyridin-3-yl)acetic acid (CAS 1805624-70-7)
- 2-(4-(Difluoromethyl)-3-fluoro-5-methoxypyridin-2-yl)acetic acid (CAS 1805624-74-1)
- 2-(Difluoromethyl)-4-fluoro-5-methoxypyridine-3-acetic acid (CAS 1806876-56-1)
- 2-(Difluoromethyl)-5-fluoro-6-methoxypyridine-3-acetic acid (CAS 1806876-62-9)
Recommended Standards
- Methyl 3-methoxy-5-(trifluoromethyl)picolinate (CAS 1804099-09-9)
- 2-(6-Methoxy-5-(trifluoromethyl)pyridin-3-yl)acetic acid (CAS 1804097-66-2)
- Ethyl 3-hydroxy-6-(trifluoromethyl)picolinate (CAS 1804096-65-8)
- Ethyl 3-hydroxy-5-(trifluoromethyl)picolinate (CAS 1803855-22-2)
- tert-Butyl 1-oxo-2,11-diazaspiro[6.7]tetradecane-11-carboxylate (CAS 1250999-07-5)
- N-(4-((2,4-dichlorobenzyl)thio)phenyl)-2-(4-phenylpiperazin-1-yl)acetamide (CAS 763107-10-4)
- 4-chloro-6-(3-iodo-1-bicyclo[1.1.1]pentanyl)quinazoline (CAS 2374231-07-7)
- 2-Bromo-4-fluoro-5-iodopyridine (CAS 1807008-60-1)
- Ethyl 2-(((tert-butoxycarbonyl)amino)methyl)-6-fluorospiro[3.3]heptane-2-carboxylate (CAS 2715119-98-3)
- 5-Amino-DL-tryptophan (CAS 6383-69-3)
- 1-(azidomethyl)-2,4-difluorobenzene (CAS 622372-75-2)
- 4-(2-Aminoethyl)-6-chloro-7-hydroxy-2H-1-benzopyran-2-one 2,2,2-trifluoroacetate (CAS 1234064-11-9)
- 6,6-Dimethylmorpholine-2-carboxylic acid (CAS 1785088-39-2)
- Semaglutide impurity 272 (CAS CATO-C4X-2226272)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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