(2-(Difluoromethyl)-6-fluoro-3-nitropyridin-4-yl)methanamine CAS 1805196-08-0
| CAS No. | 1805196-08-0 |
| Molecular Formula | C7H6F3N3O2 |
| Molecular Weight | 221.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 221.14 g/mol gives (2-(Difluoromethyl)-6-fluoro-3-nitropyridin-4-yl)methanamine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
(2-(Difluoromethyl)-6-fluoro-3-nitropyridin-4-yl)methanamine (CAS 1805196-08-0) is a high-purity analytical reference standard with the molecular formula C7H6F3N3O2 and a molecular weight of 221.14 g/mol.
Based on its molecular formula C7H6F3N3O2, (2-(Difluoromethyl)-6-fluoro-3-nitropyridin-4-yl)methanamine contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 221.14 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H6F3N3O2 |
| Molecular Weight | 221.14 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Difluoromethyl Standards
- 4-Difluoromethyl-3-(trifluoromethyl)benzonitrile (CAS 1803729-83-0)
- 2-Difluoromethyl-5-(trifluoromethyl)benzonitrile (CAS 1803808-90-3)
- 3-Difluoromethyl-5-(trifluoromethyl)benzonitrile (CAS 1803825-95-7)
- 5-Difluoromethyl-2-(trifluoromethyl)benzonitrile (CAS 1803826-03-0)
- 2-(Difluoromethyl)-3-fluoro-6-methoxypyridine-4-carboxylic acid (CAS 1804468-42-5)
- 2-Difluoromethyl-6-(trifluoromethyl)benzonitrile (CAS 1804515-80-7)
- 3-Difluoromethyl-2-(trifluoromethyl)benzonitrile (CAS 1804515-87-4)
- 2-(Difluoromethyl)-3-fluoro-6-hydroxypyridine-5-acetic acid (CAS 1805038-12-3)
Recommended Standards
- 2-(Aminomethyl)-6-(difluoromethyl)-3-fluoro-5-nitropyridine (CAS 1804424-54-1)
- 2-(Aminomethyl)-4-(difluoromethyl)-3-fluoro-5-nitropyridine (CAS 1806932-80-8)
- N-Methyl-3-nitro-5-(trifluoromethyl)pyridin-2-amine (CAS 175277-21-1)
- 2-(Aminomethyl)-3-(difluoromethyl)-6-fluoro-4-nitropyridine (CAS 1806974-47-9)
- 1-Hydroxy-8-(2-hydroxyethoxy)anthracene-9,10-dione (CAS 880758-61-2)
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- 4-(4-Bromophenyl)-2-(4-chlorophenyl)-4-oxobutanoic acid (CAS 344282-20-8)
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- (E)-4-Oxodec-2-enal (CAS 92464-81-8)
- 4-Chloropyrrolo[1,2-b]pyridazine-3-carboxamide (CAS 1400688-75-6)
- Tau Peptide (294-305) (human) trifluoroacetate salt (CAS 1428135-29-8)
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