4-(Difluoromethyl)-6-(hydroxymethyl)-2-iodopyridin-3-ol CAS 1805199-21-6

Purity 97%+In StockPharmaceutical Standards
CAS No.1805199-21-6
Molecular FormulaC7H6F2INO2
Molecular Weight301.03 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

4-(Difluoromethyl)-6-(hydroxymethyl)-2-iodopyridin-3-ol CAS 1805199-21-6 chemical structure

Description

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

4-(Difluoromethyl)-6-(hydroxymethyl)-2-iodopyridin-3-ol (CAS 1805199-21-6), molecular formula C7H6F2INO2 and molecular weight 301.03 g/mol, is a CATO reference standard with documented purity and traceability.

Structurally, 4-(Difluoromethyl)-6-(hydroxymethyl)-2-iodopyridin-3-ol (C7H6F2INO2) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/iodine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 4.0, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 301.03 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

Physical & Chemical Properties

Molecular FormulaC7H6F2INO2
Molecular Weight301.03 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)4.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1995
Halogen ContentF/I-containing
Nitrogen Atoms1

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