2-(Difluoromethyl)-4-hydroxy-5-iodopyridine-3-carboxylic acid CAS 1805199-86-3
| CAS No. | 1805199-86-3 |
| Molecular Formula | C7H4F2INO3 |
| Molecular Weight | 315.01 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-(Difluoromethyl)-4-hydroxy-5-iodopyridine-3-carboxylic acid (C7H4F2INO3) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/iodine substitution, an aromatic ring system. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies 2-(Difluoromethyl)-4-hydroxy-5-iodopyridine-3-carboxylic acid (CAS 1805199-86-3), a certified reference material (molecular formula C7H4F2INO3, MW 315.01 g/mol) for analytical method development and quality control.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H4F2INO3 |
| Molecular Weight | 315.01 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F/I-containing |
| Nitrogen Atoms | 1 |
Related Difluoromethyl Standards
- 2-(Difluoromethyl)-3-hydroxy-4-iodopyridine-5-carboxylic acid (CAS 1804867-45-5)
- 4-(Difluoromethyl)-6-hydroxy-5-iodonicotinic acid (CAS 1805208-19-8)
- 2-(Difluoromethyl)-5-hydroxy-3-iodopyridine-6-carboxylic acid (CAS 1805453-42-2)
- 2-(Difluoromethyl)-3-hydroxy-6-iodopyridine-5-carboxylic acid (CAS 1805535-88-9)
- 2-(Difluoromethyl)-5-hydroxy-3-iodopyridine-4-carboxylic acid (CAS 1805535-94-7)
- 3-(Difluoromethyl)-6-iodo-4-nitropyridin-2-amine (CAS 1805132-55-1)
- 3-(Difluoromethyl)-6-iodo-5-nitropyridin-2-amine (CAS 1805132-67-5)
- 5-(Difluoromethyl)-2-iodo-3-nitropyridin-4-amine (CAS 1805958-98-8)
Recommended Standards
- 4-Fluoro-3-iodo-2-(trifluoromethyl)benzonitrile (CAS 1539314-78-7)
- 1-(Difluoromethoxy)-2-iodo-4-nitrobenzene (CAS 1261776-70-8)
- 2-(Difluoromethoxy)-5-iodonitrobenzene (CAS 1261584-39-7)
- 2-(Difluoromethoxy)-3-iodonitrobenzene (CAS 1261499-84-6)
- (1-(4-Chlorophenyl)-3-(4-methoxyphenyl)-1H-pyrazol-4-yl)methanol (CAS 618441-62-6)
- 3-(4-Chlorophenyl)oxirane-2-carboxylic acid (CAS 114380-31-3)
- 1-[(3-Nitrophenyl)methyl]piperidine (CAS 59507-46-9)
- 4-[(2-Vinyl]-1-enthyne)-α,α-dimethyl-benzeneacetic Acid Methyl Ester (CAS 1159977-63-5)
- (E)-4-Cyclopropylbut-3-en-2-one (CAS 105891-18-7)
- 4,7-Dimethoxy-2,3-dihydrobenzofuran-3-amine (CAS 786624-52-0)
- 2-(5-Methylthiophen-2-yl)cyclopropane-1-carboxylic acid (CAS 455267-60-4)
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- 1-(5-Chlorothiophen-2-yl)-3-methylbutan-1-one (CAS 1094461-78-5)
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