3-Chloro-5-(chloromethyl)-4-(difluoromethyl)pyridin-2-amine CAS 1805207-97-9
| CAS No. | 1805207-97-9 |
| Molecular Formula | C7H6Cl2F2N2 |
| Molecular Weight | 227.04 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 3-Chloro-5-(chloromethyl)-4-(difluoromethyl)pyridin-2-amine (CAS 1805207-97-9), a certified reference material (molecular formula C7H6Cl2F2N2, MW 227.04 g/mol) for analytical method development and quality control.
3-Chloro-5-(chloromethyl)-4-(difluoromethyl)pyridin-2-amine (C7H6Cl2F2N2) contains a nitrile group, fluorine/chlorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), 3-Chloro-5-(chloromethyl)-4-(difluoromethyl)pyridin-2-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H6Cl2F2N2 |
| Molecular Weight | 227.04 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
- 4-Chloro-2-(chloromethyl)-1-(difluoromethoxy)benzene (CAS 1049874-11-4)
- 4-Chloro-1-[chloro(difluoro)-methoxy]-2-methyl-benzene (CAS 1404194-37-1)
- 2-Chloro-4-[chloro(difluoro)-methoxy]-1-methyl-benzene (CAS 1404194-45-1)
- 1-Chloro-2-[chloro(difluoro)-methoxy]-3-methyl-benzene (CAS 1404194-73-5)
- 4-Chloro-2-[chloro(difluoro)-methoxy]-1-methyl-benzene (CAS 1404194-99-5)
- 1-Chloro-3-[chloro(difluoro)-methoxy]-2-methyl-benzene (CAS 1404195-21-6)
- 3-Chloro-5-(chloromethyl)-6-(difluoromethyl)pyridin-2-amine (CAS 1805918-49-3)
- 4-Chloro-3-(chloromethyl)-6-(difluoromethyl)pyridin-2-amine (CAS 1805918-58-4)
Recommended Standards
- 2-(Aminomethyl)-3,5-dichloro-4-(difluoromethyl)pyridine (CAS 1804702-65-5)
- 2-(Aminomethyl)-3,4-dichloro-6-(difluoromethyl)pyridine (CAS 1805246-77-8)
- 1,2-Dichloro-4-(difluoromethoxy)-3-methylbenzene (CAS 1803833-82-0)
- (2,6-Dichloro-3-(difluoromethyl)pyridin-4-yl)methanamine (CAS 1805281-61-1)
- Methyl 4-Fluoropyridine-2-carboxylate (CAS 886371-79-5)
- 5-((5-Bromopyridin-2-yl)amino)-5-oxopentanoic acid (CAS 333304-99-7)
- (1R,2R)-Ethyl 2-aminocyclopentanecarboxylate hydrochloride (CAS 311341-93-2)
- 2-(Cyclopropylamino)-2-methylpropanamide (CAS 1170701-10-6)
- 3-(4-Propoxybenzoyl)phenyl acetate (CAS 890100-02-4)
- tert-Butyl 5-(2-((tert-butyldimethylsilyl)oxy)ethyl)thiophene-2-carboxylate (CAS 1799412-24-0)
- 3-bromo-5-(4-fluorophenyl)-1,2,4-oxadiazole (CAS 1564477-82-2)
- (4-(4-Fluorophenyl)piperazin-1-yl)(1H-imidazol-1-yl)methanone (CAS 492464-17-2)
- 3-Bromo-1h-pyrrolo[2,3-b]pyridine hydrobromide (CAS 1461713-60-9)
- Semaglutide impurity 37 (CAS CATO-C4X-222637)
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