4-Bromo-5-(difluoromethyl)-2-methylnicotinoyl chloride CAS 1805244-84-1
| CAS No. | 1805244-84-1 |
| Molecular Formula | C8H5BrClF2NO |
| Molecular Weight | 284.49 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-Bromo-5-(difluoromethyl)-2-methylnicotinoyl chloride (C8H5BrClF2NO) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine/bromine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO supplies 4-Bromo-5-(difluoromethyl)-2-methylnicotinoyl chloride (CAS 1805244-84-1), a certified reference material (molecular formula C8H5BrClF2NO, MW 284.49 g/mol) for analytical method development and quality control.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4-Bromo-5-(difluoromethyl)-2-methylnicotinoyl chloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H5BrClF2NO |
| Molecular Weight | 284.49 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F/Cl/Br-containing |
| Nitrogen Atoms | 1 |
Related Bromo Standards
- 2-Bromo-5-(chloromethyl)-4-(difluoromethyl)nicotinaldehyde (CAS 1804429-39-7)
- 2-Bromo-6-(chloromethyl)-3-(difluoromethyl)isonicotinaldehyde (CAS 1804429-45-5)
- 2-Bromo-3-(chloromethyl)-5-(difluoromethyl)isonicotinaldehyde (CAS 1805369-73-6)
- 2-Bromo-5-(chloromethyl)-6-(difluoromethyl)nicotinaldehyde (CAS 1805370-66-4)
- 4-Bromo-5-(difluoromethyl)-6-methylnicotinoyl chloride (CAS 1805376-71-9)
- 6-Bromo-4-(chloromethyl)-5-(difluoromethyl)picolinaldehyde (CAS 1805390-87-7)
- 6-Bromo-3-(chloromethyl)-5-(difluoromethyl)picolinaldehyde (CAS 1805391-51-8)
- 4-Bromo-2-(difluoromethyl)-5-methylnicotinoyl chloride (CAS 1805938-45-7)
Recommended Standards
- 2-(Bromomethyl)-4-(difluoromethyl)pyridine-3-carbonyl chloride (CAS 1805227-97-7)
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- Methyl 6-Amino-3,5-dibromopyridine-2-carboxylate (CAS 443956-21-6)
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- Ethyl 2-(4-(2,5-dihydro-1H-pyrrol-1-yl)phenyl)acetate (CAS 59235-27-7)
- Acetyl Tetrapeptide- 15 (CAS 928007-64-1)
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