2-Bromo-5-cyanonicotinic acid CAS 1805249-34-6

Purity 97%+In StockPharmaceutical Standards
CAS No.1805249-34-6
Molecular FormulaC7H3BrN2O2
Molecular Weight227.01 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-Bromo-5-cyanonicotinic acid CAS 1805249-34-6 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 227.01 g/mol gives 2-Bromo-5-cyanonicotinic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies 2-Bromo-5-cyanonicotinic acid (CAS 1805249-34-6), a certified reference material (molecular formula C7H3BrN2O2, MW 227.01 g/mol) for analytical method development and quality control.

Owing to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, bromine substitution, an aromatic ring system, 2-Bromo-5-cyanonicotinic acid is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 227.01 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 2-Bromo-5-cyanonicotinic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC7H3BrN2O2
Molecular Weight227.01 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)7.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1995
Halogen ContentBr-containing
Nitrogen Atoms2

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