2,4-Dichloro-6-(difluoromethyl)pyridine CAS 1805252-95-2
| CAS No. | 1805252-95-2 |
| Molecular Formula | C6H3Cl2F2N |
| Molecular Weight | 198.00 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2,4-Dichloro-6-(difluoromethyl)pyridine.
CATO supplies 2,4-Dichloro-6-(difluoromethyl)pyridine (CAS 1805252-95-2), a certified reference material (molecular formula C6H3Cl2F2N, MW 198.00 g/mol) for analytical method development and quality control.
Structurally, 2,4-Dichloro-6-(difluoromethyl)pyridine (C6H3Cl2F2N) contains a nitrile group, fluorine/chlorine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 4.0, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 198.00 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H3Cl2F2N |
| Molecular Weight | 198.00 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Dichloro Standards
- 2,6-Dichloro-4-(difluoromethyl)pyridine (CAS 1201675-01-5)
- 2,4-Dichloro-5-(difluoromethyl)pyridine (CAS 1256833-30-3)
- 2,3-Dichloro-4-(difluoromethyl)pyridine (CAS 1257071-85-4)
- 2,4-Dichloro-3,6-difluoroaniline (CAS 1314936-85-0)
- 3,5-Dichloro-2,6-difluoro-4-methylpyridine (CAS 1347815-16-0)
- 2,6-Dichloro-3-(difluoromethyl)pyridine (CAS 1374659-26-3)
- 2,5-Dichloro-4-(difluoromethyl)pyridine (CAS 1374659-30-9)
- 3,5-Dichloro-4-(difluoromethyl)pyridine (CAS 1374659-33-2)
Recommended Standards
- 2,3-Dichloro-6-(difluoromethyl)pyridine (CAS 1805193-58-1)
- 4,5-Dichloro-2-(difluoromethyl)pyridine (CAS 1805253-09-1)
- 3,5-Dichloro-2,6-difluoroaniline (CAS 1804420-45-8)
- 2,5-Dichloro-3,6-difluoroaniline (CAS 1806274-47-4)
- Tert-butyl 8-amino-1-azaspiro[5.5]Undecane-1-carboxylate (CAS 2306272-73-9)
- Ethyl 1-(5-acetyl-4-methylthiazol-2-yl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxylate (CAS 955964-60-0)
- BML-244 (CAS 104062-70-6)
- Ethyl 2-(benzylamino)thiazole-5-carboxylate (CAS 342394-00-7)
- 2',5'-Dimethoxy-[1,1'-biphenyl]-3-carbaldehyde (CAS 493030-93-6)
- 1-(4-Fluorophenyl)-3-azabicyclo[3.1.0]hexane-2,4-dione (CAS 66504-49-2)
- 6-Bromopyrazin-2-amine (CAS 54237-53-5)
- 2-(Aminomethyl)-5-fluorobenzonitrile (CAS 870562-71-3)
- 4-(5-(4-Chlorophenyl)-3-phenyl-1H-pyrazol-1-yl)benzenesulfonamide (CAS 78794-60-2)
- Peptide Impurity 41 (CAS CATO-CPTD788841)
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