4-(Difluoromethyl)-2-iodo-5-nitronicotinaldehyde CAS 1805261-56-6

Purity 97%+In StockPharmaceutical Standards
CAS No.1805261-56-6
Molecular FormulaC7H3F2IN2O3
Molecular Weight328.01 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

4-(Difluoromethyl)-2-iodo-5-nitronicotinaldehyde CAS 1805261-56-6 chemical structure

Description

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

4-(Difluoromethyl)-2-iodo-5-nitronicotinaldehyde (CAS 1805261-56-6), molecular formula C7H3F2IN2O3 and molecular weight 328.01 g/mol, is a CATO reference standard with documented purity and traceability.

Owing to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/iodine substitution, an aromatic ring system, 4-(Difluoromethyl)-2-iodo-5-nitronicotinaldehyde is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 328.01 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

As a certified reference material (CRM), 4-(Difluoromethyl)-2-iodo-5-nitronicotinaldehyde meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC7H3F2IN2O3
Molecular Weight328.01 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in methanol, ethanol, DMSO, water
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1995
Halogen ContentF/I-containing
Nitrogen Atoms2

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Why CATO?