3-(Difluoromethyl)-5-iodo-4-methylpicolinonitrile CAS 1805285-45-3
| CAS No. | 1805285-45-3 |
| Molecular Formula | C8H5F2IN2 |
| Molecular Weight | 294.04 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3-(Difluoromethyl)-5-iodo-4-methylpicolinonitrile.
3-(Difluoromethyl)-5-iodo-4-methylpicolinonitrile (CAS 1805285-45-3), molecular formula C8H5F2IN2 and molecular weight 294.04 g/mol, is a CATO reference standard with documented purity and traceability.
3-(Difluoromethyl)-5-iodo-4-methylpicolinonitrile (C8H5F2IN2) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/iodine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 3-(Difluoromethyl)-5-iodo-4-methylpicolinonitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H5F2IN2 |
| Molecular Weight | 294.04 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F/I-containing |
| Nitrogen Atoms | 2 |
Related Difluoromethyl Standards
- 1-(Difluoromethyl)-3-iodo-1H-indazole (CAS 1220572-58-6)
- 2-(Difluoromethyl)-5-iodo-3-methylisonicotinonitrile (CAS 1805187-06-7)
- 2-(Difluoromethyl)-5-iodopyridine-3-acetonitrile (CAS 1805315-20-1)
- 2-(4-(Difluoromethyl)-6-iodopyridin-3-yl)acetonitrile (CAS 1805319-71-4)
- 2-(4-(Difluoromethyl)-5-iodopyridin-3-yl)acetonitrile (CAS 1805319-83-8)
- 2-(4-(Difluoromethyl)-2-iodopyridin-3-yl)acetonitrile (CAS 1805333-46-3)
- 2-(Difluoromethyl)-4-iodopyridine-5-acetonitrile (CAS 1806781-45-2)
- 3-(Difluoromethyl)-6-iodo-4-methylpicolinonitrile (CAS 1807094-78-5)
Recommended Standards
- 4-Cyano-6-(difluoromethyl)-2-iodo-3-methylpyridine (CAS 1804730-04-8)
- 8-Bromo-5-fluoro-2-(trifluoromethyl)quinoline (CAS 1425335-26-7)
- 4-Bromo-8-fluoro-6-(trifluoromethyl)quinoline (CAS 1375302-41-2)
- 4-Cyano-3-(difluoromethyl)-2-iodo-5-methylpyridine (CAS 1805489-99-9)
- 5-(Aminomethyl)-6-(difluoromethyl)-3-nitropyridin-2-amine (CAS 1805225-47-1)
- 2-(1H-Indol-3-yl)cyclohexanone (CAS 68221-96-5)
- 4-(2-Fluorophenyl)-2-methyl-5-oxo-5H-indeno[1,2-b]pyridine-3-carbonitrile (CAS 371233-27-1)
- Biphenyl-2-yl-hydrazine hydrochloride (CAS 109221-95-6)
- tert-Butyl 1-(hydroxymethyl)-2-azabicyclo[2.1.1]hexane-2-carboxylate (CAS 467454-51-9)
- 3-(2-Methoxyethyl)-2-methyl-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-4(3H)-one (CAS 1710674-63-7)
- 3,4-Dichloro-5-fluorophenol (CAS 1804515-92-1)
- 5-Bromo-2-(cyclopentyloxy)pyridine (CAS 494771-68-5)
- 2,2'-Dibromo-4,4'-di-tert-Butyl-1,1'-biphenyl (CAS 70728-93-7)
- Semaglutide Impurity 15 (CAS CATO-C4X-222615)
Why CATO?
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