2-(4-(Difluoromethyl)-2-hydroxypyridin-3-yl)acetonitrile CAS 1805320-65-3
| CAS No. | 1805320-65-3 |
| Molecular Formula | C8H6F2N2O |
| Molecular Weight | 184.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO supplies 2-(4-(Difluoromethyl)-2-hydroxypyridin-3-yl)acetonitrile (CAS 1805320-65-3), a certified reference material (molecular formula C8H6F2N2O, MW 184.14 g/mol) for analytical method development and quality control.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, 2-(4-(Difluoromethyl)-2-hydroxypyridin-3-yl)acetonitrile is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 184.14 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO manufactures 2-(4-(Difluoromethyl)-2-hydroxypyridin-3-yl)acetonitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H6F2N2O |
| Molecular Weight | 184.14 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Difluoromethyl Standards
- 2-(Difluoromethyl)-1,3-benzoxazol-6-amine (CAS 1039313-16-0)
- 2-(Difluoromethyl)benzo[d]oxazol-5-amine (CAS 1039961-21-1)
- 2-(Difluoromethyl)benzo[d]oxazol-4-amine (CAS 1159528-43-4)
- 2-(Difluoromethyl)-1H-benzimidazol-1-ol (CAS 1211514-60-1)
- 2-(difluoromethyl)-1H-benzimidazol-4-ol (CAS 1336890-16-4)
- 3-(Difluoromethyl)-6-hydroxy-2-methylisonicotinonitrile (CAS 1804490-54-7)
- 3-(Difluoromethyl)-4-methoxypicolinonitrile (CAS 1804759-55-4)
- 3-(Difluoromethyl)-2-(hydroxymethyl)isonicotinonitrile (CAS 1805004-80-1)
Recommended Standards
- 4-(Difluoromethyl)-3-(hydroxymethyl)picolinonitrile (CAS 1805318-72-2)
- 4-Cyano-2-(difluoromethyl)-5-hydroxy-3-methylpyridine (CAS 1805356-46-0)
- 3-(Difluoromethyl)-6-methoxypicolinonitrile (CAS 1805305-34-3)
- 3-(Difluoromethyl)-5-hydroxy-4-methylpicolinonitrile (CAS 1805422-14-3)
- 2-(Pyridin-2-yl)-1-(pyridin-3-yl)ethan-1-amine (CAS 58088-75-8)
- 4-(Difluoromethyl)-5-fluoro-3-iodopyridin-2-amine (CAS 1805113-42-1)
- 1-Fluoro-3-methoxy-5-(methoxymethoxy)benzene (CAS 2432848-99-0)
- Fmoc-(Fmoc-Hmb)-Lys(Boc)-OH (CAS 166881-56-7)
- 2-(Prop-1-en-2-yl)tetrahydrofuran-3-carboxylic acid (CAS 1823247-28-4)
- Baclofen Impurity 59 (CAS CATO-C4X-101259)
- 4-(6-Hydroxypyrimidin-4-yl)-1-methylpyrrolidin-2-one (CAS 1707735-26-9)
- 1-(4-Nitrophenyl)-1h-benzo[d]imidazole (CAS 22492-14-4)
- 5-(2-(3-Methoxyphenoxy)ethyl)-1,3,4-thiadiazol-2-amine (CAS 878656-33-8)
- Des-Ser39-Tirzepatide (CAS CATO-CPTD788936)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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