4-(Difluoromethyl)-6-fluoropyridine-2-sulfonamide CAS 1805321-96-3

Description

The occurrence of 4-(Difluoromethyl)-6-fluoropyridine-2-sulfonamide is closely related to an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

4-(Difluoromethyl)-6-fluoropyridine-2-sulfonamide (CAS 1805321-96-3), molecular formula C6H5F3N2O2S and molecular weight 226.18 g/mol, is a CATO reference standard with documented purity and traceability.

4-(Difluoromethyl)-6-fluoropyridine-2-sulfonamide (C6H5F3N2O2S) contains an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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