4-Amino-5-(difluoromethyl)-6-hydroxypicolinaldehyde CAS 1805327-89-2

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-Amino-5-(difluoromethyl)-6-hydroxypicolinaldehyde.

4-Amino-5-(difluoromethyl)-6-hydroxypicolinaldehyde (CAS 1805327-89-2) is a high-purity analytical reference standard with the molecular formula C7H6F2N2O2 and a molecular weight of 188.13 g/mol.

Based on its molecular formula C7H6F2N2O2, 4-Amino-5-(difluoromethyl)-6-hydroxypicolinaldehyde contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 188.13 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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