(6-Amino-4-(aminomethyl)-5-(difluoromethyl)pyridin-2-yl)methanol CAS 1805336-45-1
| CAS No. | 1805336-45-1 |
| Molecular Formula | C8H11F2N3O |
| Molecular Weight | 203.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
(6-Amino-4-(aminomethyl)-5-(difluoromethyl)pyridin-2-yl)methanol (CAS 1805336-45-1) is a high-purity analytical reference standard with the molecular formula C8H11F2N3O and a molecular weight of 203.19 g/mol.
The molecular framework of (6-Amino-4-(aminomethyl)-5-(difluoromethyl)pyridin-2-yl)methanol (C8H11F2N3O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), (6-Amino-4-(aminomethyl)-5-(difluoromethyl)pyridin-2-yl)methanol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H11F2N3O |
| Molecular Weight | 203.19 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Amino Standards
- 1-amino-3-(3,4-difluorophenoxy)propan-2-ol (CAS 1157091-16-1)
- (s)-2-Amino-2-(2-(difluoromethoxy)phenyl)ethan-1-ol (CAS 1212960-38-7)
- (r)-2-Amino-2-(2-(difluoromethoxy)phenyl)ethan-1-ol (CAS 1213103-75-3)
- (s)-2-Amino-2-(4,5-difluoro-2-methoxyphenyl)ethan-1-ol (CAS 1213162-01-6)
- (s)-2-Amino-2-(3,5-difluoro-2-methoxyphenyl)ethan-1-ol (CAS 1213323-80-8)
- (s)-2-Amino-2-(3-(difluoromethoxy)phenyl)ethan-1-ol (CAS 1213434-05-9)
- (r)-2-Amino-2-(3,5-difluoro-2-methoxyphenyl)ethan-1-ol (CAS 1213553-83-3)
- (r)-2-Amino-2-(4-(difluoromethoxy)phenyl)ethan-1-ol (CAS 1213855-52-7)
Recommended Standards
- (4-(Difluoromethyl)-5-methoxy-6-methylpyridin-3-yl)methanol (CAS 1805149-20-5)
- (2-Amino-4-(aminomethyl)-5-(difluoromethyl)pyridin-3-yl)methanol (CAS 1805344-41-5)
- 2-(Difluoromethyl)-3,6-dimethoxy-5-methylpyridine (CAS 1804943-27-8)
- (4-Amino-6-(aminomethyl)-5-(difluoromethyl)pyridin-2-yl)methanol (CAS 1805385-92-5)
- Ethyl tetrahydro-4-oxo-2-furancarboxylate (CAS 2089377-51-3)
- Methyl (E)-3-(3,5-dichlorophenyl)acrylate (CAS 695187-25-8)
- 7-Nitro-5H-pyrrolo[3,2-d]pyrimidine-4-carboxylic acid (CAS 916213-56-4)
- 1-[1-[2-Oxo-2-(1,2,5-trimethyl-3-pyrrolyl)ethyl]-4-piperidinyl]-1H-benzo[d]imidazol-2(3H)-one (CAS 924108-75-8)
- 3-Methoxy-6-phenylsulfonyl-6,7-didehydro Estradiol (CAS 153004-08-1)
- 1,5,6,7-Tetrahydro-2H-pyrrolo[2,3-d]pyrimidine-2,4(3H)-dione 2,2,2-trifluoroacetate (CAS 16372-12-6)
- 5,6,7,8-Tetrahydro-1,7-naphthyridin-2(1H)-one (CAS 1196154-84-3)
- tert-Butyl 2-(1-mercaptoethyl)piperidine-1-carboxylate (CAS 1420976-03-9)
- 4-Cyclopropoxy-2-ethylbenzaldehyde (CAS 1243443-65-3)
- Semaglutide Impurity 147 (CAS CATO-C4X-2226147)
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