2-Bromo-3-(chloromethyl)-6-(difluoromethyl)-4-nitropyridine CAS 1805378-91-9
| CAS No. | 1805378-91-9 |
| Molecular Formula | C7H4BrClF2N2O2 |
| Molecular Weight | 301.47 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-Bromo-3-(chloromethyl)-6-(difluoromethyl)-4-nitropyridine.
2-Bromo-3-(chloromethyl)-6-(difluoromethyl)-4-nitropyridine (CAS 1805378-91-9) is a high-purity analytical reference standard with the molecular formula C7H4BrClF2N2O2 and a molecular weight of 301.47 g/mol.
Based on its molecular formula C7H4BrClF2N2O2, 2-Bromo-3-(chloromethyl)-6-(difluoromethyl)-4-nitropyridine contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine/bromine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 301.47 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2-Bromo-3-(chloromethyl)-6-(difluoromethyl)-4-nitropyridine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H4BrClF2N2O2 |
| Molecular Weight | 301.47 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F/Cl/Br-containing |
| Nitrogen Atoms | 2 |
Related Bromo Standards
- 2-Bromo-6-(chloromethyl)-5-(difluoromethyl)-3-nitropyridine (CAS 1804671-34-8)
- 2-Bromo-5-(chloromethyl)-3-(difluoromethyl)-4-nitropyridine (CAS 1805249-37-9)
- 2-Bromo-6-(chloromethyl)-3-(difluoromethyl)-5-nitropyridine (CAS 1805340-63-9)
- 2-Bromo-5-(chloromethyl)-4-(difluoromethyl)-3-nitropyridine (CAS 1805357-93-0)
- 2-Bromo-5-(chloromethyl)-6-(difluoromethyl)-3-nitropyridine (CAS 1806921-47-0)
- 2-Bromo-1-(3-chloro-4-(trifluoromethyl)phenyl)ethan-1-one (CAS 129322-86-7)
- 3-Bromo-5-chloro-4-(trifluoromethyl)acetophenone (CAS 1804384-44-8)
- 6-Bromo-3-chloro-2-(trifluoromethyl)acetophenone (CAS 1804384-53-9)
Recommended Standards
- 2-(Bromomethyl)-6-chloro-3-(difluoromethyl)-5-nitropyridine (CAS 1805385-85-6)
- 2-(Bromomethyl)-6-chloro-4-(difluoromethyl)-3-nitropyridine (CAS 1806041-11-1)
- 2-(Bromomethyl)-3-chloro-6-(difluoromethyl)-4-nitropyridine (CAS 1806871-05-5)
- 2-(Bromomethyl)-5-chloro-4-(difluoromethyl)-3-nitropyridine (CAS 1806895-18-0)
- Ethyl 2-amino-4-methylfuran-3-carboxylate (CAS 1505673-54-0)
- N-Biotinyl-4,7,10-trioxa-1,13-tridecanediamine trifluoroacetate, 96% (CAS 1334172-59-6)
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- n-(3-Tert-butyl-1-methyl-1h-pyrazol-5-yl)-2-chloroacetamide (CAS 1211120-75-0)
- 3,5-Difluoropyridine-2-carboxylic acid dimethylamide (CAS 1245215-73-9)
- 1-Methyl-4-phenylcyclohexan-1-ol (CAS 94734-13-1)
- 4-(2-Chlorophenyl)-2-methylthiazole (CAS 777853-12-0)
- Peptide Impurity 11 X TFA Salt (CAS CATO-CPTD788811)
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