2-Chloro-6-(cyanomethyl)-3-(difluoromethyl)isonicotinonitrile CAS 1805394-63-1
| CAS No. | 1805394-63-1 |
| Molecular Formula | C9H4ClF2N3 |
| Molecular Weight | 227.60 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 227.60 g/mol gives 2-Chloro-6-(cyanomethyl)-3-(difluoromethyl)isonicotinonitrile distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 2-Chloro-6-(cyanomethyl)-3-(difluoromethyl)isonicotinonitrile (CAS 1805394-63-1), a certified reference material (molecular formula C9H4ClF2N3, MW 227.60 g/mol) for analytical method development and quality control.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution, 2-Chloro-6-(cyanomethyl)-3-(difluoromethyl)isonicotinonitrile is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 227.60 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 2-Chloro-6-(cyanomethyl)-3-(difluoromethyl)isonicotinonitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C9H4ClF2N3 |
| Molecular Weight | 227.60 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloro Standards
- 3-Chloro-6-methoxy-4-nitro-1H-indazole (CAS 1000341-15-0)
- 6-Chloro-3-oxo-3,4-dihydro-2H-benzo[b][1,4]oxazine-8-carboxylic acid (CAS 123040-45-9)
- 2-Chloro-n-[5-(furan-2-yl)-1,3,4-oxadiazol-2-yl]acetamide (CAS 1354952-25-2)
- 2-Chloro-6-(cyanomethyl)-5-(difluoromethyl)nicotinonitrile (CAS 1804465-03-9)
- 4-Chloro-3-(cyanomethyl)-6-(difluoromethyl)picolinonitrile (CAS 1804665-98-2)
- 2-Chloro-5-(cyanomethyl)-3-(difluoromethyl)isonicotinonitrile (CAS 1804853-99-3)
- 4-Chloro-6-(cyanomethyl)-5-(difluoromethyl)picolinonitrile (CAS 1805051-46-0)
- 6-Chloro-5-(cyanomethyl)-4-(difluoromethyl)picolinonitrile (CAS 1805260-18-7)
Recommended Standards
- 4-Chloro-2-(cyanomethyl)-5-(difluoromethyl)nicotinonitrile (CAS 1805388-86-6)
- 6-Chloro-3-(cyanomethyl)-5-(difluoromethyl)picolinonitrile (CAS 1805973-08-3)
- 2-(Carboxy(hydroxy)methyl)-4-chlorobenzo[d]oxazole (CAS 1806488-51-6)
- 6-Chloro-2-(cyanomethyl)-5-(difluoromethyl)nicotinonitrile (CAS 1806869-10-2)
- 3-[(propan-2-yloxy)methyl]-1-benzofuran-2-carboxylic acid (CAS 731802-25-8)
- 1-(5-Bromothiophen-2-yl)-3-cyclopropylpropane-1,3-dione (CAS 1267403-87-1)
- 5-[(3-methoxyphenyl)amino]-1,3,4-thiadiazole-2-thiol (CAS 68161-58-0)
- 2-(2,3-Dihydro-9H-benzo[d]imidazo[1,2-a]imidazol-9-yl)-N,N-dimethylethan-1-amine (CAS 64644-54-8)
- (2s)-2-Amino-2-methyl-3-sulfanylpropanoic acid hydrochloride (CAS 151062-55-4)
- N1,N2-Bis(4-methoxyphenyl)-1-methylhydrazine-1,2-bis(carbothioamide) (CAS 455880-00-9)
- (R)-4-Methyloxazolidin-2-one (CAS 4042-43-7)
- DIBENZYLIDENE ETHYLENEDIAMINE (CAS 174707-18-7)
- 1-(5-Bromo-3-chloropyridin-2-yl)ethanamine (CAS 749201-00-1)
- Semaglutide impurity 247 (CAS CATO-C4X-2226247)
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