6-Bromo-2-(difluoromethyl)-5-fluoropyridin-3-ol CAS 1805401-46-0
| CAS No. | 1805401-46-0 |
| Molecular Formula | C6H3BrF3NO |
| Molecular Weight | 241.99 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 6-Bromo-2-(difluoromethyl)-5-fluoropyridin-3-ol is closely related to an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 6-Bromo-2-(difluoromethyl)-5-fluoropyridin-3-ol (CAS 1805401-46-0), a certified reference material (molecular formula C6H3BrF3NO, MW 241.99 g/mol) for analytical method development and quality control.
Based on its molecular formula C6H3BrF3NO, 6-Bromo-2-(difluoromethyl)-5-fluoropyridin-3-ol contains an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 241.99 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 6-Bromo-2-(difluoromethyl)-5-fluoropyridin-3-ol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H3BrF3NO |
| Molecular Weight | 241.99 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 1 |
Related Bromo Standards
- 3-Bromo-5-(trifluoromethoxy)pyridine (CAS 1060815-01-1)
- 3-Bromo-2-(trifluoromethoxy)pyridine (CAS 1086393-00-1)
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- 5-Bromo-2-(trifluoromethyl)pyridin-4-ol (CAS 1196156-74-7)
- 2-Bromo-4-(trifluoromethoxy)pyridine (CAS 1206977-89-0)
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- 2-Bromo-3-hydroxy-4-(trifluoromethyl)pyridine (CAS 1211526-19-0)
- 2-Bromo-6-(trifluoromethyl)pyridin-3-ol (CAS 1211526-50-9)
Recommended Standards
- 6-Bromo-5-(difluoromethyl)-4-fluoropyridin-2-ol (CAS 1805401-02-8)
- 2-Bromo-4-difluoromethoxy-3-fluoropyridine (CAS 1805525-88-5)
- 4-Bromo-5-(difluoromethyl)-6-fluoropyridin-3-ol (CAS 1805392-90-8)
- 6-Bromo-3-difluoromethoxy-2-fluoropyridine (CAS 1805526-29-7)
- 1020054-14-1 7527AC C17H20N2O2 N-(5-Amino-2-methylphenyl)-3-propoxybenzamide (CAS 1020054-14-1)
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