(4-Chloro-5-(difluoromethyl)-6-methoxypyridin-2-yl)methanol CAS 1805404-40-3
| CAS No. | 1805404-40-3 |
| Molecular Formula | C8H8ClF2NO2 |
| Molecular Weight | 223.60 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (4-Chloro-5-(difluoromethyl)-6-methoxypyridin-2-yl)methanol.
CATO supplies (4-Chloro-5-(difluoromethyl)-6-methoxypyridin-2-yl)methanol (CAS 1805404-40-3), a certified reference material (molecular formula C8H8ClF2NO2, MW 223.60 g/mol) for analytical method development and quality control.
Based on its molecular formula C8H8ClF2NO2, (4-Chloro-5-(difluoromethyl)-6-methoxypyridin-2-yl)methanol contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 223.60 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures (4-Chloro-5-(difluoromethyl)-6-methoxypyridin-2-yl)methanol under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H8ClF2NO2 |
| Molecular Weight | 223.60 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 2-Chloro-5,6,7-trifluorobenzo[d]thiazole (CAS 1245053-34-2)
- 2-Chloro-4,5,6-trifluorobenzo[d]thiazole (CAS 1245213-27-7)
- 2-Chloro-4,5,7-trifluorobenzo[d]thiazole (CAS 1379336-88-5)
- (4-Chloro-2-(difluoromethyl)-6-methoxypyridin-3-yl)methanol (CAS 1804370-89-5)
- (4-Chloro-5-(difluoromethyl)-2-methoxypyridin-3-yl)methanol (CAS 1804370-90-8)
- 4-Chloro-3-(difluoromethyl)-2,5-dimethoxypyridine (CAS 1805159-58-3)
- (6-Chloro-2-(difluoromethyl)-5-methoxypyridin-3-yl)methanol (CAS 1805262-90-1)
- 4-Chloro-2-(difluoromethyl)-3,6-dimethoxypyridine (CAS 1805324-52-0)
Recommended Standards
- 2-(Chloromethyl)-4-(difluoromethyl)-3-hydroxypyridine-5-methanol (CAS 1805402-23-6)
- 2-(Chloromethyl)-3-(difluoromethyl)-5-hydroxy-4-methoxypyridine (CAS 1805450-27-4)
- 2-(Chloromethyl)-6-(difluoromethyl)-3-hydroxypyridine-4-methanol (CAS 1805396-14-8)
- 2-(Chloromethyl)-4-(difluoromethyl)-3-hydroxy-6-methoxypyridine (CAS 1805450-39-8)
- 2,3-Dihydrobenzofuran-6-thiol (CAS 90590-08-2)
- 3-Amino-N-(3-fluorophenyl)propanamide (CAS 938517-17-0)
- N-(4-Fluoro-3-methylbenzo[d]thiazol-2(3H)-ylidene)-4-methoxybenzamide (CAS 868371-21-5)
- 2,4-Dimethoxy-5-nitropyrimidine (CAS 30561-07-0)
- 4-Bromo-1-isobutyl-1h-1,2,3-triazole (CAS 1393558-23-0)
- 8-Methoxyimidazo[1,2-a]pyridine-6-carboxylic acid hydrochloride (CAS 2060033-77-2)
- tert-Butyl 2-({[2-(isopropylamino)-2-oxoethyl]amino}carbonyl)-1-hydrazinecarboxylate (CAS 1424940-87-3)
- Diethyl 1-amino-3-methyl-1H-pyrrole-2,4-dicarboxylate (CAS 427878-69-1)
- 2-butyl-2-phenyl-hexanenitrile 2-butyl-2-phenylhexanenitrile 3975-14-2 A824724 (CAS 3975-14-2)
- Tau Peptide (337-368) (Repeat 4 Domain) trifluoroacetate salt (CAS 330456-27-4)
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