2-Bromo-5-(difluoromethyl)-4-iodopyridine-3-sulfonamide CAS 1805422-74-5
| CAS No. | 1805422-74-5 |
| Molecular Formula | C6H4BrF2IN2O2S |
| Molecular Weight | 412.98 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
2-Bromo-5-(difluoromethyl)-4-iodopyridine-3-sulfonamide (CAS 1805422-74-5) is a high-purity analytical reference standard with the molecular formula C6H4BrF2IN2O2S and a molecular weight of 412.98 g/mol.
The molecular framework of 2-Bromo-5-(difluoromethyl)-4-iodopyridine-3-sulfonamide (C6H4BrF2IN2O2S) is characterized by an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/bromine/iodine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), 2-Bromo-5-(difluoromethyl)-4-iodopyridine-3-sulfonamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H4BrF2IN2O2S |
| Molecular Weight | 412.98 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F/Br/I-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Bromo Standards
- 6-Bromo-5-(difluoromethyl)-4-iodopyridine-3-sulfonamide (CAS 1804464-09-2)
- 4-Bromo-6-(difluoromethyl)-5-iodopyridine-3-sulfonamide (CAS 1805245-63-9)
- 2-Bromo-6-(difluoromethyl)-4-iodopyridine-3-sulfonamide (CAS 1805347-55-0)
- 2-Bromo-5-(difluoromethyl)-3-iodopyridine-4-sulfonamide (CAS 1805379-37-6)
- 4-Bromo-2-(difluoromethyl)-5-iodopyridine-3-sulfonamide (CAS 1805379-61-6)
- 6-Bromo-2-(difluoromethyl)-5-iodopyridine-3-sulfonamide (CAS 1805422-83-6)
- 6-Bromo-5-(difluoromethyl)-4-iodopyridine-2-sulfonamide (CAS 1805918-68-6)
- 6-Bromo-5-(difluoromethyl)-3-iodopyridine-2-sulfonamide (CAS 1807028-22-3)
Recommended Standards
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- 3-Iodo-5-methylthiophene (CAS 16494-35-2)
- 2-(3,5-Dibromo-1H-1,2,4-triazol-1-yl)-1-[4-(trifluoromethyl)phenyl]ethan-1-one (CAS 1240568-21-1)
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