2-Bromo-5-(difluoromethyl)-3-methoxypyridine-4-sulfonamide CAS 1805427-84-2
| CAS No. | 1805427-84-2 |
| Molecular Formula | C7H7BrF2N2O3S |
| Molecular Weight | 317.11 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-Bromo-5-(difluoromethyl)-3-methoxypyridine-4-sulfonamide.
2-Bromo-5-(difluoromethyl)-3-methoxypyridine-4-sulfonamide (CAS 1805427-84-2), molecular formula C7H7BrF2N2O3S and molecular weight 317.11 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-Bromo-5-(difluoromethyl)-3-methoxypyridine-4-sulfonamide (C7H7BrF2N2O3S) is characterized by an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-Bromo-5-(difluoromethyl)-3-methoxypyridine-4-sulfonamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H7BrF2N2O3S |
| Molecular Weight | 317.11 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Bromo Standards
- 6-Bromo-5-(difluoromethyl)-4-methoxypyridine-3-sulfonamide (CAS 1804463-61-3)
- 4-Bromo-3-(difluoromethyl)-2-methoxypyridine-5-sulfonamide (CAS 1805168-63-1)
- 6-Bromo-5-(difluoromethyl)-3-methoxypyridine-2-sulfonamide (CAS 1805242-76-5)
- 4-Bromo-6-(difluoromethyl)-5-methoxypyridine-3-sulfonamide (CAS 1805340-16-2)
- 2-Bromo-4-(difluoromethyl)-5-methoxypyridine-3-sulfonamide (CAS 1805351-94-3)
- 2-Bromo-3-(difluoromethyl)-6-methoxypyridine-4-sulfonamide (CAS 1805427-79-5)
- 2-Bromo-6-(difluoromethyl)-5-methoxypyridine-3-sulfonamide (CAS 1805428-16-3)
- 4-Bromo-2-(difluoromethyl)-6-methoxypyridine-3-sulfonamide (CAS 1805428-69-6)
Recommended Standards
- 4-Bromo-6-(difluoromethyl)-2-methoxypyridine-3-sulfonamide (CAS 1805428-79-8)
- 4-Bromo-3-(difluoromethyl)-6-methoxypyridine-2-sulfonamide (CAS 1805428-85-6)
- 6-Bromo-5-(difluoromethyl)-2-methoxypyridine-3-sulfonamide (CAS 1806906-02-4)
- 4-Bromo-5-(difluoromethyl)-3-methoxypyridine-2-sulfonamide (CAS 1806908-55-3)
- Methyl 2-[4-(2-bromoethoxy)phenyl]acetate (CAS 100125-95-9)
- N-(2-Oxo-1,2,3,4-tetrahydroquinolin-3-yl)acetamide (CAS 716-91-6)
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- 4-fluorocyclohexanecarbaldehyde (CAS 1554041-53-0)
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