2-(Difluoromethyl)-4-fluoro-3-iodopyridine-5-sulfonamide CAS 1805439-89-7

Purity 97%+In StockPharmaceutical Standards
CAS No.1805439-89-7
Molecular FormulaC6H4F3IN2O2S
Molecular Weight352.07 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-(Difluoromethyl)-4-fluoro-3-iodopyridine-5-sulfonamide CAS 1805439-89-7 chemical structure

Description

2-(Difluoromethyl)-4-fluoro-3-iodopyridine-5-sulfonamide (CAS 1805439-89-7) is a high-purity analytical reference standard with the molecular formula C6H4F3IN2O2S and a molecular weight of 352.07 g/mol.

Based on its molecular formula C6H4F3IN2O2S, 2-(Difluoromethyl)-4-fluoro-3-iodopyridine-5-sulfonamide contains an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/iodine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 352.07 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 2-(Difluoromethyl)-4-fluoro-3-iodopyridine-5-sulfonamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC6H4F3IN2O2S
Molecular Weight352.07 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)4.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1995
Halogen ContentF/I-containing
Nitrogen Atoms2
Sulfur Atoms1

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