2-(Difluoromethyl)-3-methoxy-4-nitropyridine-6-methanol CAS 1805465-62-6
| CAS No. | 1805465-62-6 |
| Molecular Formula | C8H8F2N2O4 |
| Molecular Weight | 234.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 234.16 g/mol gives 2-(Difluoromethyl)-3-methoxy-4-nitropyridine-6-methanol distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 2-(Difluoromethyl)-3-methoxy-4-nitropyridine-6-methanol (CAS 1805465-62-6), a certified reference material (molecular formula C8H8F2N2O4, MW 234.16 g/mol) for analytical method development and quality control.
2-(Difluoromethyl)-3-methoxy-4-nitropyridine-6-methanol (C8H8F2N2O4) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H8F2N2O4 |
| Molecular Weight | 234.16 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Difluoromethyl Standards
- 2-(Difluoromethyl)-4,6-dimethoxy-3-nitropyridine (CAS 1804695-73-5)
- 4-(Difluoromethyl)-3,5-dimethoxy-2-nitropyridine (CAS 1805050-05-8)
- 2-(Difluoromethyl)-3-methoxy-5-nitropyridine-6-methanol (CAS 1805068-48-7)
- 2-(Difluoromethyl)-5-methoxy-3-nitropyridine-4-methanol (CAS 1805068-55-6)
- 4-(Difluoromethyl)-2,3-dimethoxy-5-nitropyridine (CAS 1805257-89-9)
- 2-(Difluoromethyl)-3,5-dimethoxy-4-nitropyridine (CAS 1805258-11-0)
- 2-(Difluoromethyl)-3-methoxy-5-nitropyridine-4-methanol (CAS 1805434-85-8)
- 2-(Difluoromethyl)-5-methoxy-4-nitropyridine-3-methanol (CAS 1805465-70-6)
Recommended Standards
- 2-(Difluoromethyl)-6-methoxy-4-nitropyridine-3-methanol (CAS 1805554-57-7)
- 4-(Difluoromethyl)-2,5-dimethoxy-3-nitropyridine (CAS 1806802-51-6)
- 2-(Difluoromethyl)-3,4-dimethoxy-5-nitropyridine (CAS 1806820-53-0)
- 2-(Difluoromethyl)-3-methoxy-4-nitropyridine-5-methanol (CAS 1807137-76-3)
- Di-O-benzyl Relmapirazin (CAS CATO-C4X-33343)
- 2,5-Bis(5,5-dimethyl-1,3,2-dioxaborinan-2-yl)thiophene (CAS 26076-47-1)
- 2-Bromo-3-phenylbutanenitrile (CAS 1018986-05-4)
- 1-Butyl-3-vinyl-3-imidazolium Bis[(trifluoromethyl)sulfonyl]amide Homopolymer (CAS 1007390-44-4)
- 1-{3-oxa-6-azatricyclo[6.1.1.0¹,⁶]decan-4-yl}methanamine (CAS 1989672-87-8)
- (2S,3aS,6R,7aS)-3a-Methyl-2-((perfluorophenyl)thio)-6-(prop-1-en-2-yl)hexahydrobenzo[d][1,3,2]oxathiaphosphole 2-sulfide (CAS 2245335-70-8)
- 2-(dimethoxymethyl)-6-(methylamino)pyridine-3-carbaldehyde (CAS 2227206-52-0)
- (S)-1-Boc-3-(Hydroxymethyl)pyrrolidine (CAS 199174-24-8)
- 2-(Piperidin-4-yl)-6-(pyridin-3-yl)-[1,2,4]triazolo[1,5-a]pyridine (CAS 1422138-53-1)
- Peptide 437 (CAS CATO-CPTD788437)
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