4-(Difluoromethyl)-2-hydroxy-6-iodopyridine-3-sulfonamide CAS 1805480-65-2

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-(Difluoromethyl)-2-hydroxy-6-iodopyridine-3-sulfonamide.

4-(Difluoromethyl)-2-hydroxy-6-iodopyridine-3-sulfonamide (CAS 1805480-65-2) is a high-purity analytical reference standard with the molecular formula C6H5F2IN2O3S and a molecular weight of 350.08 g/mol.

4-(Difluoromethyl)-2-hydroxy-6-iodopyridine-3-sulfonamide (C6H5F2IN2O3S) contains an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/iodine substitution, an aromatic ring system. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 4-(Difluoromethyl)-2-hydroxy-6-iodopyridine-3-sulfonamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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