2-(Chloromethyl)-6-(difluoromethyl)-5-hydroxypyridine-3-carboxylic acid CAS 1805503-63-2
| CAS No. | 1805503-63-2 |
| Molecular Formula | C8H6ClF2NO3 |
| Molecular Weight | 237.59 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-(Chloromethyl)-6-(difluoromethyl)-5-hydroxypyridine-3-carboxylic acid.
CATO supplies 2-(Chloromethyl)-6-(difluoromethyl)-5-hydroxypyridine-3-carboxylic acid (CAS 1805503-63-2), a certified reference material (molecular formula C8H6ClF2NO3, MW 237.59 g/mol) for analytical method development and quality control.
Structurally, 2-(Chloromethyl)-6-(difluoromethyl)-5-hydroxypyridine-3-carboxylic acid (C8H6ClF2NO3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 237.59 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 2-(Chloromethyl)-6-(difluoromethyl)-5-hydroxypyridine-3-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H6ClF2NO3 |
| Molecular Weight | 237.59 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloromethyl Standards
- 4-(Chloromethyl)-5-(difluoromethyl)-3-nitropyridin-2-amine (CAS 1804685-52-6)
- 6-(Chloromethyl)-3-(difluoromethyl)-4-nitropyridin-2-amine (CAS 1804685-61-7)
- 2-(Chloromethyl)-6-(difluoromethyl)-3-hydroxypyridine-5-carboxylic acid (CAS 1805092-05-0)
- 6-(Chloromethyl)-5-(difluoromethyl)-3-nitropyridin-2-amine (CAS 1805353-90-5)
- 2-(Chloromethyl)-3-(difluoromethyl)-4-hydroxypyridine-5-carboxylic acid (CAS 1805541-54-1)
- 2-(Chloromethyl)-5-(difluoromethyl)-3-hydroxypyridine-4-carboxylic acid (CAS 1805609-04-4)
- 2-(Chloromethyl)-5-(difluoromethyl)-3-hydroxypyridine-6-carboxylic acid (CAS 1805999-13-6)
- 2-(Chloromethyl)-6-(difluoromethyl)-4-hydroxypyridine-3-carboxylic acid (CAS 1805999-18-1)
Recommended Standards
- 2-(Difluoromethyl)-6-hydroxy-3-methoxypyridine-4-carbonyl chloride (CAS 1805485-07-7)
- Methyl 6-chloro-2-(difluoromethoxy)nicotinate (CAS 1805519-87-2)
- 2-(Difluoromethyl)-5-hydroxy-3-methoxypyridine-6-carbonyl chloride (CAS 1805485-01-1)
- 2-(Difluoromethyl)-4-hydroxy-3-methoxypyridine-6-carbonyl chloride (CAS 1805530-12-4)
- (5-Amino-2,4-difluorophenyl)boronic acid (CAS 1072952-05-6)
- 1H-Pyrrolo[3,2-c]pyridine-2-carboxylic acid ethyl ester hydrochloride (CAS 1187929-10-7)
- 2,4-Difluoro-5-methylbenzotrifluoride (CAS 1263377-03-2)
- 2-((1-(Furan-2-ylmethyl)-1H-imidazol-2-yl)thio)-N-(4-methylthiazol-2-yl)acetamide (CAS 872594-29-1)
- 3-(1H-imidazol-1-yl)-N-(4-(methylthio)benzyl)propan-1-amine (CAS 797770-11-7)
- tert-Butyl 9-(4-amino-2-methoxyphenyl)-3,9-diazaspiro[5.5]undecane-3-carboxylate (CAS 1453211-89-6)
- Methyl 4-Bromo-3-(2-bromophenyl)-1H-pyrazole-5-carboxylate (CAS 1239225-43-4)
- 4,6-Dichloro-2-(ethoxymethyl)pyrimidine (CAS 3122-82-5)
- 2-Chloro-N-(2,4,5-trichlorophenyl)propanamide (CAS 379254-97-4)
- Peptide T (CAS 106362-32-7)
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