2-(Difluoromethyl)-6-methoxy-3-(trifluoromethyl)pyridine-4-carboxaldehyde CAS 1805549-81-8
| CAS No. | 1805549-81-8 |
| Molecular Formula | C9H6F5NO2 |
| Molecular Weight | 255.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
2-(Difluoromethyl)-6-methoxy-3-(trifluoromethyl)pyridine-4-carboxaldehyde (CAS 1805549-81-8) is a high-purity analytical reference standard with the molecular formula C9H6F5NO2 and a molecular weight of 255.14 g/mol.
2-(Difluoromethyl)-6-methoxy-3-(trifluoromethyl)pyridine-4-carboxaldehyde (C9H6F5NO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO manufactures 2-(Difluoromethyl)-6-methoxy-3-(trifluoromethyl)pyridine-4-carboxaldehyde under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C9H6F5NO2 |
| Molecular Weight | 255.14 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Difluoromethyl Standards
- 2-(Difluoromethyl)-6-(trifluoromethyl)pyridine-4-acetic acid (CAS 1416822-08-6)
- 2-(Difluoromethyl)-5-methoxy-3-(trifluoromethyl)pyridine-4-carboxaldehyde (CAS 1804870-44-7)
- 4-(Difluoromethyl)-5-methoxy-6-(trifluoromethyl)nicotinaldehyde (CAS 1804870-94-7)
- 4-(Difluoromethyl)-2-methoxy-6-(trifluoromethyl)nicotinaldehyde (CAS 1805073-50-0)
- 2-(Difluoromethyl)-3-(trifluoromethyl)pyridine-6-acetic acid (CAS 1805316-73-7)
- 4-(Difluoromethyl)-2-methoxy-5-(trifluoromethyl)nicotinaldehyde (CAS 1805438-43-0)
- 2-(Difluoromethyl)-5-methoxy-6-(trifluoromethyl)pyridine-3-carboxaldehyde (CAS 1805549-77-2)
- 4-(Difluoromethyl)-6-methoxy-3-(trifluoromethyl)picolinaldehyde (CAS 1805622-26-7)
Recommended Standards
- 2-(Difluoromethyl)-5-(trifluoromethyl)pyridine-3-acetic acid (CAS 1805946-86-4)
- 2-(4-(Difluoromethyl)-2-(trifluoromethyl)pyridin-3-yl)acetic acid (CAS 1805947-10-7)
- 2-(4-(Difluoromethyl)-3-(trifluoromethyl)pyridin-2-yl)acetic acid (CAS 1805947-20-9)
- 6-(Difluoromethyl)-2-methoxy-5-(trifluoromethyl)nicotinaldehyde (CAS 1806956-57-9)
- 2-(4-Isopropylphenyl)cyclohexan-1-ol (CAS 197704-79-3)
- (5-Chlorobenzo[d][1,3]dioxol-4-yl)boronic acid (CAS 2087452-50-2)
- (11bS)-2,6-Di-9-anthracenyl-N,N-bis[(1R)-1-phenylethyl]dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin-4-amine (CAS 1622095-62-8)
- 3-Amino-3-hydroxymethyloxetane (CAS 1305208-37-0)
- 2-(Difluoromethyl)-6-(trifluoromethyl)pyridine-4-carbonyl chloride (CAS 1804693-63-7)
- 6-Ethyl-3-methoxy-2-methylphenol (CAS 859821-26-4)
- 6-Chloro-9-(4-chlorobut-2-yn-1-yl)-9H-purin-2-amine (CAS 121653-93-8)
- 1-Amino-2-bromo-4-hydroxyanthracene-9,10-dione (CAS 116-82-5)
- (E)-4-((4-Fluorobenzyl)amino)-4-oxobut-2-enoic acid (CAS 863647-67-0)
- Cyclopeptide-5 (CAS 197172-76-2)
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