4-(Difluoromethyl)-3-methyl-5-nitropicolinoyl chloride CAS 1805554-78-2

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-(Difluoromethyl)-3-methyl-5-nitropicolinoyl chloride.

4-(Difluoromethyl)-3-methyl-5-nitropicolinoyl chloride (CAS 1805554-78-2) is a high-purity analytical reference standard with the molecular formula C8H5ClF2N2O3 and a molecular weight of 250.59 g/mol.

Structurally, 4-(Difluoromethyl)-3-methyl-5-nitropicolinoyl chloride (C8H5ClF2N2O3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 250.59 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 4-(Difluoromethyl)-3-methyl-5-nitropicolinoyl chloride under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

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