2-Bromo-4-(difluoromethyl)-5-nitropyridine CAS 1805593-76-3

Purity 97%+In StockPharmaceutical Standards
CAS No.1805593-76-3
Molecular FormulaC6H3BrF2N2O2
Molecular Weight253.00 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-Bromo-4-(difluoromethyl)-5-nitropyridine CAS 1805593-76-3 chemical structure

Description

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

2-Bromo-4-(difluoromethyl)-5-nitropyridine (CAS 1805593-76-3), molecular formula C6H3BrF2N2O2 and molecular weight 253.00 g/mol, is a CATO reference standard with documented purity and traceability.

2-Bromo-4-(difluoromethyl)-5-nitropyridine (C6H3BrF2N2O2) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/bromine substitution, an aromatic ring system. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

Physical & Chemical Properties

Molecular FormulaC6H3BrF2N2O2
Molecular Weight253.00 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1995
Halogen ContentF/Br-containing
Nitrogen Atoms2

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