4-Amino-3-fluoropicolinamide CAS 1805876-54-3
| CAS No. | 1805876-54-3 |
| Molecular Formula | C6H6FN3O |
| Molecular Weight | 155.13 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 4-Amino-3-fluoropicolinamide (C6H6FN3O) is characterized by an amide group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
4-Amino-3-fluoropicolinamide (CAS 1805876-54-3) is a high-purity analytical reference standard with the molecular formula C6H6FN3O and a molecular weight of 155.13 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-Amino-3-fluoropicolinamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H6FN3O |
| Molecular Weight | 155.13 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Amino Standards
- 5-Amino-6-fluoro-1,3-benzodioxole (CAS 1366234-03-8)
- 5-Amino-6-fluoropyridine-3-carboxamide (CAS 1378738-56-7)
- 2-Amino-3-fluoroisonicotinamide (CAS 1595881-31-4)
- 6-amino-2-fluoronicotinamide (CAS 175357-99-0)
- 2-Amino-5-fluoropyridine-4-carboxamide (CAS 1803896-21-0)
- 3-Amino-2-fluoropyridine-4-carboxamide (CAS 1804052-83-2)
- 3-Amino-5-fluoropicolinamide (CAS 1804146-01-7)
- 5-Amino-3-fluoropicolinamide (CAS 1804171-45-6)
Recommended Standards
- 5-Amino-4-fluoropyridine-2-carboxamide (CAS 1805741-38-1)
- 3-Amino-5-fluoroisonicotinamide (CAS 1806511-38-5)
- 3-Amino-4-fluoropicolinamide (CAS 1805741-35-8)
- 4-Amino-5-fluoropicolinamide (CAS 1806682-21-2)
- 3-(2,4-Dichlorophenyl)-5,6,7,8-tetrahydro-5,8-methanocinnoline (CAS 918875-07-7)
- (E)-1-(4-(tert-butyl)benzyl)-2-(2-chlorostyryl)-1H-benzo[d]imidazole (CAS 338772-11-5)
- 4-Iodo-N-propylbenzenesulfonamide (CAS 403793-14-6)
- 3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyridin-8-amine (CAS 1539410-06-4)
- N1-butyl-N1-methylbenzene-1,2-diamine (CAS 1016727-11-9)
- Hexyl 2-(5-fluoro-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)acetate (CAS 174582-14-0)
- 5-Chloro-1-(2-chlorophenyl)-1H-pyrazole-4-carbonitrile (CAS 102996-34-9)
- 4-(2-METHYL-1,3-DIOXOLAN-2-YL)PYRIDIN-2-AMINE (CAS 80882-44-6)
- N,N-Dimethyl-2-phenylpyrimidin-5-amine (CAS 921939-11-9)
- Semaglutide Impurity 8 (CAS CATO-C4X-22268)
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