2-Amino-6-(difluoromethyl)-4-iodonicotinonitrile CAS 1805927-94-9
| CAS No. | 1805927-94-9 |
| Molecular Formula | C7H4F2IN3 |
| Molecular Weight | 295.03 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-Amino-6-(difluoromethyl)-4-iodonicotinonitrile (CAS 1805927-94-9), molecular formula C7H4F2IN3 and molecular weight 295.03 g/mol, is a CATO reference standard with documented purity and traceability.
2-Amino-6-(difluoromethyl)-4-iodonicotinonitrile (C7H4F2IN3) contains a nitrile group, fluorine/iodine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H4F2IN3 |
| Molecular Weight | 295.03 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F/I-containing |
| Nitrogen Atoms | 3 |
Related Amino Standards
- 2-Amino-5-(difluoromethyl)-6-iodonicotinonitrile (CAS 1803698-86-3)
- 2-Amino-4-(difluoromethyl)-6-iodonicotinonitrile (CAS 1804699-37-3)
- 2-Amino-4-(difluoromethyl)-5-iodonicotinonitrile (CAS 1805056-23-8)
- 6-Amino-5-(difluoromethyl)-4-iodonicotinonitrile (CAS 1805111-45-8)
- 2-Amino-3-(difluoromethyl)-5-iodoisonicotinonitrile (CAS 1805349-28-3)
- 4-Amino-3-(difluoromethyl)-5-iodopicolinonitrile (CAS 1805928-12-4)
- 4-Amino-3-(difluoromethyl)-6-iodopicolinonitrile (CAS 1806835-45-9)
- 2-Amino-5-(difluoromethyl)-4-iodonicotinonitrile (CAS 1806839-58-6)
Recommended Standards
- 4-Amino-5-(difluoromethyl)-3-iodopicolinonitrile (CAS 1806840-32-3)
- 5-Iodo-6-methoxy-3-nitropyridin-2-amine (CAS 868539-54-2)
- N-(5-Iodo-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)acetamide (CAS 138481-93-3)
- 6-(Difluoromethyl)-3-iodoimidazo[1,2-b]pyridazine (CAS 2366182-84-3)
- 1-(piperidin-4-yl)-1,3-diazinan-2-one (CAS 61220-36-8)
- N,N-Dimethyldecan-1-amine oxide (CAS 2605-79-0)
- [5-(1-ADamantyl)-2-methylphenyl]amine hydrochloride (CAS 59974-07-1)
- 4-(3-(4-Chloro-5,6-dimethyl-7H-pyrrolo[2,3-d]pyrimidin-7-yl)propyl)morpholine (CAS 869220-79-1)
- (R)-tert-Butyl 2-(hydroxymethyl)-1,4-oxazepane-4-carboxylate (CAS 911223-23-9)
- 3-Bromo-4-isopropoxyphenylacetic Acid (CAS 1522661-29-5)
- 4-((4-Chlorobenzylidene)amino)benzenesulfonamide (CAS 105947-03-3)
- 3,5-Dimethoxy-4-((4-methylbenzyl)oxy)benzaldehyde (CAS 1154653-85-6)
- N-(4-(3,4-Dihydroisoquinolin-2(1H)-yl)but-2-yn-1-yl)-4-methylthiophene-2-carboxamide (CAS 1351596-47-8)
- Peptide-GMF (CAS CATO-CPTD788469)
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