2-Bromo-4-fluoro-6-nitropyridine CAS 1805938-41-3
| CAS No. | 1805938-41-3 |
| Molecular Formula | C5H2BrFN2O2 |
| Molecular Weight | 220.98 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies 2-Bromo-4-fluoro-6-nitropyridine (CAS 1805938-41-3), a certified reference material (molecular formula C5H2BrFN2O2, MW 220.98 g/mol) for analytical method development and quality control.
The molecular framework of 2-Bromo-4-fluoro-6-nitropyridine (C5H2BrFN2O2) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C5H2BrFN2O2 |
| Molecular Weight | 220.98 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 2 |
Related Bromo Standards
- 3-Bromo-5-fluoro-2-nitropyridine (CAS 1258544-91-0)
- 4-Bromo-2-fluoro-5-nitropyridine (CAS 1335114-94-7)
- 2-Bromo-3-fluoro-5-nitropyridine (CAS 1353100-68-1)
- 6-Bromo-2-fluoro-3-nitropyridine (CAS 1417333-87-9)
- 5-Bromo-3-fluoro-2-nitropyridine (CAS 1532517-95-5)
- 2-Bromo-6-fluoro-3-nitropyridine (CAS 1639977-00-6)
- 4-Bromo-3-fluoro-5-nitropyridine (CAS 1804407-56-4)
- 4-Bromo-2-fluoro-6-nitropyridine (CAS 1805152-15-1)
Recommended Standards
- 4-Bromo-3-fluoro-2-nitropyridine (CAS 1805578-63-5)
- 2-bromo-3-fluoro-4-nitropyridine (CAS 1807072-92-9)
- 3-Bromo-4-fluoro-5-nitropyridine (CAS 1805578-57-7)
- 5-Bromo-4-fluoro-2-nitropyridine (CAS 1807183-67-0)
- Tetrakis(2-(octyldisulfanyl)ethyl) 3,3',3'',3'''-(((methylazanediyl)bis(ethane-2,1-diyl))bis(azanetriyl))tetrapropionate (CAS 2803699-72-9)
- Boc-Gly-Gly-Phe-Gly-OH (CAS 187794-49-6)
- 4-Bromo-2-chloro-1-ethenyl-benzene (CAS 943742-24-3)
- N-(3-(Furan-2-yl)allylidene)-1-phenylmethanamine (CAS 108493-68-1)
- Varenicline Impurity C61 (CAS 357424-12-5)
- N-Cyclopentyl-5,6-diphenylpyridazin-3-amine (CAS 562103-96-2)
- (5-Fluoro-1-methyl-2-oxo-2,3-dihydro-1H-indol-3-yl)acetic acid 2045AF 887405-60-9 C11H10FNO3 (CAS 887405-60-9)
- (1S,2S,4R)-2-aminobicyclo[2.2.1]Heptane-2-carboxylic acid (CAS 39669-35-7)
- 3',4'-Dimethyl-[1,1'-biphenyl]-4-carboxylic acid (CAS 122294-09-1)
- Semaglutide Impurity 183 (CAS 159541-28-3)
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