4-Chloro-3-(difluoromethyl)-5-hydroxypicolinonitrile CAS 1805971-11-2

Purity 97%+In StockPharmaceutical Standards
CAS No.1805971-11-2
Molecular FormulaC7H3ClF2N2O
Molecular Weight204.56 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

4-Chloro-3-(difluoromethyl)-5-hydroxypicolinonitrile CAS 1805971-11-2 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-Chloro-3-(difluoromethyl)-5-hydroxypicolinonitrile.

CATO supplies 4-Chloro-3-(difluoromethyl)-5-hydroxypicolinonitrile (CAS 1805971-11-2), a certified reference material (molecular formula C7H3ClF2N2O, MW 204.56 g/mol) for analytical method development and quality control.

Structurally, 4-Chloro-3-(difluoromethyl)-5-hydroxypicolinonitrile (C7H3ClF2N2O) contains an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 204.56 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 4-Chloro-3-(difluoromethyl)-5-hydroxypicolinonitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC7H3ClF2N2O
Molecular Weight204.56 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1995
Halogen ContentF/Cl-containing
Nitrogen Atoms2

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