2-(Difluoromethyl)-3-fluoro-4-nitropyridine-6-carboxaldehyde CAS 1805985-74-3
| CAS No. | 1805985-74-3 |
| Molecular Formula | C7H3F3N2O3 |
| Molecular Weight | 220.11 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-(Difluoromethyl)-3-fluoro-4-nitropyridine-6-carboxaldehyde.
2-(Difluoromethyl)-3-fluoro-4-nitropyridine-6-carboxaldehyde (CAS 1805985-74-3) is a high-purity analytical reference standard with the molecular formula C7H3F3N2O3 and a molecular weight of 220.11 g/mol.
2-(Difluoromethyl)-3-fluoro-4-nitropyridine-6-carboxaldehyde (C7H3F3N2O3) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2-(Difluoromethyl)-3-fluoro-4-nitropyridine-6-carboxaldehyde meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H3F3N2O3 |
| Molecular Weight | 220.11 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Difluoromethyl Standards
- 2-(Difluoromethyl)-6-fluoro-4-nitropyridine-3-carboxaldehyde (CAS 1805289-54-6)
- 2-(Difluoromethyl)-6-fluoro-3-nitropyridine-4-carboxaldehyde (CAS 1805436-88-7)
- 2-(Difluoromethyl)-5-fluoro-3-nitropyridine-4-carboxaldehyde (CAS 1805475-27-7)
- 4-(Difluoromethyl)-5-fluoro-3-nitropicolinaldehyde (CAS 1805605-96-2)
- 2-(Difluoromethyl)-4-fluoro-3-nitropyridine-6-carboxaldehyde (CAS 1805985-80-1)
- 2-(Difluoromethyl)-5-fluoro-3-nitropyridine-6-carboxaldehyde (CAS 1806987-90-5)
- 4-(Difluoromethyl)-6-fluoro-3-nitropicolinaldehyde (CAS 1807129-80-1)
- 4,6-Bis(difluoromethyl)-2-hydroxynicotinonitrile (CAS 869945-81-3)
Recommended Standards
- 7-bromoimidazo[1,2-a]pyridin-5-amine (CAS 1822620-44-9)
- 7-bromo-3-methyl-3H-imidazo[4,5-c]pyridine (CAS 1784125-40-1)
- 7-bromo-1-methyl-pyrazolo[4,3-b]pyridine (CAS 1823268-58-1)
- 3-bromo-1-methyl-pyrazolo[4,3-c]pyridine (CAS 1781091-10-8)
- N-(1-Cyanocyclopentyl)-3-fluorobenzamide (CAS 912770-81-1)
- 4-Hydroxy-2-phenylpyridine (CAS 883107-55-9)
- N-(2-Methoxyethyl)benzene-1,4-diamine DiHCl (CAS 72584-59-9)
- 2-(3,4-Dihydroxyphenyl)-3-hydroxy-6-propyl-4H-chromen-4-one (CAS 1313738-79-2)
- 5-Bromo-6-methyl-1,3-benzoxazole (CAS 1321599-77-2)
- 2-Chloro-6,7-dihydrothieno[2',3':4,5]oxepino[3,2-b]pyridine-9-carboxylic acid (CAS 1282528-90-8)
- tert-butyl (3S)-3-methyl-5-oxo-morpholine-4-carboxylate (CAS 2632993-39-4)
- 1-((5-Methyl-1,3,4-thiadiazol-2-yl)thio)butan-2-amine (CAS 869943-31-7)
- Fluticasone Impurity 36 (CAS 192191-51-8)
- Semaglutide impurity 202 (CAS CATO-C4X-2226202)
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